Category: 15164-44-0

The author of 《R-Benzylidenehydrazides of NH-Furoyl-5-Iodoanthranilic Acids: Synthesis, Properties, and Analgesic and Antibacterial Activity》 were Gazizova, A. F.; Kurbatov, E. R.; Makhmudov, R. R.; Bobyleva, A. A.; Korkodinova, L. M.; Kurbatova, A. A.. And the article was published in Pharmaceutical Chemistry Journal in 2019. Synthetic Route of C7H5IO The author mentioned the following in the article:

A series of R-benzylidenehydrazides of NH-furoyl-5-iodoanthranilic acid were synthesized by condensing NH-furoyl-5-iodoanthranilic acid hydrazide with aromatic aldehydes. Their structures were confirmed using IR and PMR spectroscopy. Their analgesic and antibacterial activities were studied. The results came from multiple reactions, including the reaction of 4-Iodobenzaldehyde(cas: 15164-44-0Synthetic Route of C7H5IO)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Synthetic Route of C7H5IO

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Novel D-π-A type near-infrared fluorescent probes for the detection of Aβ40 aggregates》 was written by Lv, Guanglei; Xu, Yunze; Yang, Jiajia; Li, Wenhui; Li, Chunxia; Sun, Anyang. Synthetic Route of C7H5IO And the article was included in Analyst (Cambridge, United Kingdom) in 2020. The article conveys some information:

Aberrant accumulation of Amyloid-β (Aβ) peptide is closely related to Alzheimer′s disease. Thus, it is important to develop featured probes for the specific detection of Aβ species. Herein, the authors designed and synthesized a novel near-IR fluorescent probe SDPY based on the D-π-A architecture for the detection of Aβ aggregates. The probe SDPY displayed higher affinity for Aβ40 aggregates over Aβ42 aggregates in solution (Kd = 164 nM vs. 2.1 μM). In addition, SDPY showed excellent anti-interference against a wide range of other substances. Furthermore, SDPY was capable of labeling Aβ40 aggregates better than Aβ42 aggregates in the brain sections of AD transgenic mouse models.4-Iodobenzaldehyde(cas: 15164-44-0Synthetic Route of C7H5IO) was used in this study.

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Synthetic Route of C7H5IO

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Microwave-Assisted Synthesis of N-Substituted Maleimide Derivatives as Exogenous Antioxidant Agents》 were Rammohan, Aluru; Mallikarjuna Reddy, Guda; Raul Garcia, Jarem; Zyryanov, Grigory V.; Sravya, Gundala; Bakthavatchala Reddy, Nemallapudi; Yuvaraja, Gutha. And the article was published in Journal of Heterocyclic Chemistry in 2019. SDS of cas: 15164-44-0 The author mentioned the following in the article:

A series of N-substituted maleimide derivatives I [R = H, 4-F, 4-CF3, 4-MeO, 3-Cl, 2-H2N, etc.] have been developed via acetic acid-mediated microwave reaction pathway, which was identified as the incomparable method for this maleimide compounds All the synthesized compounds were tested for antioxidant activity by DPPH and H2O2 methods. Compounds I [R = 4-MeO, 2-H2N] displayed higher antioxidant activity in both methods. The structure-activity relationship demonstrated that the compounds I [R = 4-MeO, 2-H2N] having electron releasing substitutions, generally show more beneficial activity than electron capture substitution cores. Thus, compounds I [R = 4-MeO, 2-H2N] may be useful as an exogenous antioxidant. The results came from multiple reactions, including the reaction of 4-Iodobenzaldehyde(cas: 15164-44-0SDS of cas: 15164-44-0)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.SDS of cas: 15164-44-0

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Enantio- and Regioselective NiH-Catalyzed Reductive Hydroarylation of Vinylarenes with Aryl Iodides》 was written by He, Yuli; Liu, Chuang; Yu, Lei; Zhu, Shaolin. Application In Synthesis of 4-Iodobenzaldehyde And the article was included in Angewandte Chemie, International Edition in 2020. The article conveys some information:

A highly enantio- and regioselective hydroarylation process of vinylarenes with aryl halides has been developed using a NiH catalyst and a new chiral bis imidazoline ligand. A broad range of structurally diverse, enantio-enriched 1,1-diarylalkanes, a structure found in a number of biol. active mols., have been obtained with excellent yields and enantio-selectivities under extremely mild conditions. In the experiment, the researchers used 4-Iodobenzaldehyde(cas: 15164-44-0Application In Synthesis of 4-Iodobenzaldehyde)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Application In Synthesis of 4-Iodobenzaldehyde

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Tang, Ying-Jie; Fang, Wen-Le; Ren, Kui; Guo, Xiao-Feng; Wang, Hong published an article in 2021. The article was titled 《A turn-on homodimer fluorescent probe based on homo-FRET for the sensing of biothiols in lysosome: a trial of a new turn-on strategy》, and you may find the article in Analyst (Cambridge, United Kingdom).HPLC of Formula: 15164-44-0 The information in the text is summarized as follows:

Fluorescence resonance energy transfer (FRET) is often applied to construct fluorescent probes for acquiring high selectivity and sensitivity. According to the FRET theory, a homodimer composed of two identical fluorophores with a small Stokes shift has only weak fluorescence due to homo-FRET between fluorophores, and the fluorescence could be recovered after the destruction of the homodimer. In this study, we designed and synthesized a homodimer fluorescent probe, namely 1,3,5,7-tetramethyl-8-(4′-phenylthiophenol)-boron difluoride-dipyrrole methane dimer (D-TMSPB), based on this turn-on strategy. In D-TMSPB, the disulfide moiety was selected as the response moiety of biothiols, and BODIPY fluorophore was chosen as both donor and acceptor in FRET due to the ultra-small Stokes shifts and obvious overlap of its excitation/emission peak. D-TMSPB exhibited only weak fluorescence. After selective reaction with biothiols, FRET was destroyed and the derivative exhibited strong fluorescence at 514 nm with the limit of detection of about 0.15 μM for GSH. Notably, the derivative of biothiols shows remarkable fluorescence only in acidic conditions, which accords with the internal environment of lysosome. Thus, D-TMSPB was applied to image the biothiols of lysosome in living cells. The turn-on fluorescence of D-TMSPB indicated that homo-FRET is a practical strategy to design turn-on fluorescent probes, particularly for the sensing mechanism based on leaving groups.4-Iodobenzaldehyde(cas: 15164-44-0HPLC of Formula: 15164-44-0) was used in this study.

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.HPLC of Formula: 15164-44-0

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Wang, Xiu; Pan, Shitao; Luo, Qinyu; Wang, Qian; Ni, Chuanfa; Hu, Jinbo published an article in Journal of the American Chemical Society. The title of the article was 《Controllable Single and Double Difluoromethylene Insertions into C-Cu Bonds: Copper-Mediated Tetrafluoroethylation and Hexafluoropropylation of Aryl Iodides with TMSCF2H and TMSCF2Br》.Electric Literature of C7H5IO The author mentioned the following in the article:

The selective difluoromethylene insertion into a C-Cu bond is a challenging task and is currently limited to either a single CF2 insertion into CuCF3 or double CF2 insertions into CuC6F5 (or (Z)-CF3CF = CFCu). Achieving both selective single and double CF2 insertions into the same C-Cu bond is even more difficult. Herein, highly controllable single and double CF2 insertions into CuCF2H species with a TMSCF2Br reagent have been described, affording two previously unknown fluoroalkylcopper species “”Cu(CF2)nCF2H”” (n = 1 and 2) independently under different reaction conditions. This work represents the first example of both single and double CF2 insertions into the same C-Cu bond in a highly selective manner. The synthetic value of the obtained “”Cu(CF2)nCF2H”” (n = 1 and 2) species is demonstrated by their reactions with aryl iodides, halogenation agents, and cinnamyl chloride, which enables the direct transfer of HCF2CF2 and HCF2CF2CF2 moieties into organic mols. The key to controllable fluorocarbon chain elongation from C1 to C2 and from C1 to C3 is presumably attributed to the different reactivities of “”Cu(CF2)nCF2H”” species (n = 0, 1, 2 and 3) and the loading of the TMSCF2Br reagent. In the experiment, the researchers used many compounds, for example, 4-Iodobenzaldehyde(cas: 15164-44-0Electric Literature of C7H5IO)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Electric Literature of C7H5IO

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Regio- and Stereoselective Synthesis of Ynenamides through Gold(I)-Catalyzed Hydroalkynylation of Ynamides》 was written by Siera, Hannah; Kreuzahler, Mathis; Wolper, Christoph; Haberhauer, Gebhard. Name: 4-IodobenzaldehydeThis research focused onynenamide preparation regioselective stereoselective DFT; gold catalyst ynamide hydroalkynylation. The article conveys some information:

Herein, regio- and stereoselective preparation of ynenamides I [R = Pr, cyclopropyl, Ph, etc.] via gold(I)-catalyzed hydroalkynylation of ynamides was exptl. shown. A wide range of products could be generated with yields up to 90% and, in contrast to many other gold-catalyzed alkyne dimerization reactions, alkyl groups were tolerated. Quantum chem. calculations and NMR labeling experiments revealed a mechanism via dual gold catalysis. In the part of experimental materials, we found many familiar compounds, such as 4-Iodobenzaldehyde(cas: 15164-44-0Name: 4-Iodobenzaldehyde)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Name: 4-Iodobenzaldehyde

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Wang, Hepan; Zheng, Purui; Wu, Xiaoqiang; Li, Yuqiang; Xu, Tao published an article in Journal of the American Chemical Society. The title of the article was 《Modular and Facile Access to Chiral α-Aryl Phosphates via Dual Nickel- and Photoredox-Catalyzed Reductive Cross-Coupling》.Reference of 4-Iodobenzaldehyde The author mentioned the following in the article:

Chiral phosphine-containing skeletons are important motifs in bioactive natural products, pharmaceuticals, chiral catalysts, and ligands. Herein, the authors report a general and modular platform to access chiral α-aryl P compounds via a Ni/photoredox-catalyzed enantioconvergent reductive cross-coupling between α-bromophosphates and aryl iodides. This dual catalytic regime exhibited high efficiency and good functional group capacity. A wide variety of substrates bearing a diverse set of functional groups could be converted into chiral phosphates in good to excellent yields and enantioselectivities. The utility of the method was also demonstrated by the development of a new phosphine ligand and the synthesis of enzyme inhibitor derivatives The detailed mechanistic studies supported a radical chain process and revealed a unique distinction compared with traditional reductive cross-coupling. The experimental process involved the reaction of 4-Iodobenzaldehyde(cas: 15164-44-0Reference of 4-Iodobenzaldehyde)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Reference of 4-Iodobenzaldehyde

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Asymmetric Three-Component Heck Arylation/Amination of Nonconjugated Cyclodienes》 was published in Angewandte Chemie, International Edition in 2020. These research results belong to Zhu, Daoyong; Jiao, Zhiwei; Chi, Yonggui Robin; Goncalves, Theo P.; Huang, Kuo-Wei; Zhou, Jianrong Steve. Product Details of 15164-44-0 The article mentions the following:

Substituted cyclohexylamines are becoming increasingly important in drug discovery. Asym. Heck insertion/amination of nonconjugated cyclodienes proceeds to give 5-aryl cyclohexenylamines with good enantioselectivity and exclusive trans configurations. Primary and secondary anilines, indoline, and benzylamines are suitable amines. The weakly donating diphosphite Kelliphite forms a deep unsym. pocket, which is essential for stereoselective anti attack of amines. In the experiment, the researchers used many compounds, for example, 4-Iodobenzaldehyde(cas: 15164-44-0Product Details of 15164-44-0)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Product Details of 15164-44-0

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Tali, Javeed Ahmad; Singh, Davinder; Kumar, Gulshan; Shankar, Ravi published their research in Asian Journal of Organic Chemistry in 2021. The article was titled 《Regioselective Base-controlled Pd-catalyzed Arylation of Imidazo[1,2-a]pyridines: leading selectivity at C8 position by N-chelation over O-chelation》.Safety of 4-Iodobenzaldehyde The article contains the following contents:

Herein, Pd/Ag2CO3 promoted C8 arylation of the heterocycles I (R = H, Me, Cl; R1 = H, Me, Cl; R2 = H; R3 = CHO) by overriding the N-chelation on O-chelation to form diarylimidazo[1,2-a]pyridine-carbaldehydes I (R2 = Ph, 3,4-dichlorophenyl, 4-formylphenyl, etc.; R3 = CHO) was reported. In this way, various examples have been synthesized in good to excellent yield. Furthermore, Pd/t-BuOK system has been developed for the novel deformylative C3 arylation of 2-aryl-imidazo[1,2-a]pyridines I to form diarylimidazo[1,2-a]pyridines I (R2 = H; R3 = Ph, 3,4-dichlorophenyl, 4-formylphenyl, etc.). The choice of the catalytic system is also demonstrated for heteroarylation. Both standardized protocols have been explored with broad substrate scope and good functional group tolerance. The experimental part of the paper was very detailed, including the reaction process of 4-Iodobenzaldehyde(cas: 15164-44-0Safety of 4-Iodobenzaldehyde)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Safety of 4-Iodobenzaldehyde

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com