Category: 15164-44-0

Wang, Qian; Gong, Haiying; Zhang, Yifang; Peng, Yi; Chen, Hua; Li, Mingjie; Deng, Hongmei; Hao, Jian; Wan, Wen published their research in Organic & Biomolecular Chemistry in 2021. The article was titled 《Visible-light mediated stereospecific C(sp2)-H difluoroalkylation of (Z)-aldoximes》.COA of Formula: C7H5IO The article contains the following contents:

A visible light mediated stereospecific C(sp2)-H difluoroalkylation of (Z)-aldoximes to (E)-difluoroalkylated ketoximes was described. In this reaction, (hetero)-aromatic and aliphatic difluoroalkylated ketoximes could be obtained with the retention of the configuration of the starting aldoximes. A preliminary mechanism study showed that a difluoromethyl radical via an SET pathway was involved. After reading the article, we found that the author used 4-Iodobenzaldehyde(cas: 15164-44-0COA of Formula: C7H5IO)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.COA of Formula: C7H5IO

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Thanetchaiyakup, Adisak; Borwornpinyo, Suparerk; Rattanarat, Hassayaporn; Kanjanasirirat, Phongthon; Jearawuttanakul, Kedchin; Seemakhan, Sawinee; Chuanopparat, Nutthawat; Ngernmeesri, Paiboon published an article in 2021. The article was titled 《Copper-catalyzed synthesis and anticancer activity evaluation of indolo[1,2-a]quinoline derivatives》, and you may find the article in Tetrahedron Letters.Application of 15164-44-0 The information in the text is summarized as follows:

A simple and effective one-pot synthesis of substituted indolo[1,2-a]quinolines I (R = CHO, CN; R1 = H, Me, Cl, F, etc.; R2 = H, Me, Ph) has been developed. The desired products I were obtained in up to 98% yield when substituted 2-methyindoles II were treated with 2-iodobenzaldehyde in the presence of Cs2CO3, CuI and L-proline. The mechanistic study confirmed that the reaction sequence involved an intermol. Knoevenagel reaction followed by an intramol. Ullmann-type coupling reaction. Moreover, some of the synthesized compounds I were found to be active against human breast (MCF-7) and colorectal (HCT-116) cancer cells with IC50 values of 27.96μM and in the range of 6.21-46.91μM, resp. In the experimental materials used by the author, we found 4-Iodobenzaldehyde(cas: 15164-44-0Application of 15164-44-0)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Application of 15164-44-0

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Yang, Xiaogang; Lu, Dong; Guan, Wenjian; Yin, Shuang-Feng; Kambe, Nobuaki; Qiu, Renhua published an article in Journal of Organic Chemistry. The title of the article was 《Synthesis of (Deoxy)difluoromethylated Phosphines by Reaction of R2P(O)H with TMSCF3 and Their Application in Cu(I) Clusters in Sonogashira Coupling》.Reference of 4-Iodobenzaldehyde The author mentioned the following in the article:

R2PCF2H ligands and their R2P(O)CF2H precursors were synthesized from R2P(O)H with TMSCF3 by simply modulating the H2O concentration via deoxydifluoromethylation and difluoromethylation. The air sensitive R2PCF2H phosphines can be stabilized in Cu(I) clusters as ligands. Within these Cu(I) clusters, the Sonogashira cross-coupling reaction can proceed fast and efficiently using terminal alkynes and aryl iodides within 15 min at room temperature under air to give a variety of diaryl(alkyl)acetylenes in good yields (49 examples, yields of ≤99%). Six of the internal alkynes present in drug precursors can be obtained using this protocol in good yields. The mechanism is proposed from control experiments The experimental process involved the reaction of 4-Iodobenzaldehyde(cas: 15164-44-0Reference of 4-Iodobenzaldehyde)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Reference of 4-Iodobenzaldehyde

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,Journal of Organic Chemistry included an article by Xiang, Jia-Chen; Wu, Zhi-Jie; Gu, Qing; You, Shu-Li. Formula: C7H5IO. The article was titled 《Palladium-Catalyzed C-H Diarylation of Ferrocenecarboxylic Acids with Aryl Iodides》. The information in the text is summarized as follows:

Palladium-catalyzed C-H diarylation of ferrocenes is described. In the presence of 10 mol% Pd(OAc)2, direct C-H diarylation reactions of com. available ferrocenecarboxylic acid with aryl iodides proceeded smoothly to afford diarylated ferrocenes bearing a variety of functional groups in moderate to good yields. The carboxylic group could also act as a remote directing group to result in the third arylation on the other Cp ring of ferrocene.4-Iodobenzaldehyde(cas: 15164-44-0Formula: C7H5IO) was used in this study.

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Formula: C7H5IO

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《A selective and highly sensitive high performance liquid chromatography with fluorescence derivatization approach based on Sonogashira coupling reaction for determination of ethinyl estradiol in river water samples》 was published in Journal of Chromatography A in 2020. These research results belong to Ali, Marwa F. B.; Uejo, Yurina; Kishikawa, Naoya; Ohyama, Kaname; Kuroda, Naotaka. Electric Literature of C7H5IO The article mentions the following:

A selective and highly sensitive high performance liquid chromatog. (HPLC) with fluorescence derivatization method was developed for determination of ethinyl estradiol (EE); one of endocrine-disrupting compounds (EDCs). The fluorescence derivatization procedure was based on Sonogashira coupling reaction using 4-(4, 5-diphenyl-1H-imidazole-2-yl) iodobenzene (DIB-I), a fluorescence labeling reagent, to derivatize EE in presence of copper and palladium ions. The formed fluorescent product was separated on Cosmosil 5C18 MS-II by an isocratic elution with a mobile phase composed of acetonitrile: 5.0 mM Tris-HNO3 buffer, pH 7.4 (60:40, volume/volume %). The detection wavelengths were set at 310 and 400 nm as excitation and emission wavelengths, resp. Various parameters affecting derivatization reaction were optimized. Further, the proposed method was validated and a good linearity with low detection limit (S/N=3) 7.4 ng L-1 was obtained in water sample after a simple solid-phase disk extraction (C18 SPE disk) method. The proposed method was successfully applied for detection of EE in river water samples in order to monitor EE concentration and to distinguish its effect on the ecosystem and human health. The experimental process involved the reaction of 4-Iodobenzaldehyde(cas: 15164-44-0Electric Literature of C7H5IO)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Electric Literature of C7H5IO

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Waki, Minoru; Inagaki, Shinji published an article in 2021. The article was titled 《Metal scavenging and catalysis by periodic mesoporous organosilicas with 2,2′-bipyridine metal chelating ligands》, and you may find the article in Applied Organometallic Chemistry.Recommanded Product: 15164-44-0 The information in the text is summarized as follows:

A periodic mesoporous organosilica containing 2,2′-bipyridine (BPy-PMO) was assessed as a metal scavenger and heterogeneous catalyst. The functionalized PMO was synthesized based on a modified version of a previously reported procedure and showed a large surface area with crystal-like pore walls and uniformly small particles. The small BPy-PMOs (s-BPy-PMOs) exhibited efficient adsorption and removal of palladium (Pd2+) and copper (Cu2+) ions from THF solutions, as confirmed by inductively coupled plasma and UV/vis spectroscopy analyses. The removal efficiencies for Pd and Cu were determined to be 99.9% and 97.5%, resp. This material was also used to scavenge residual Pd and Cu from reagent solutions following Sonogashira-Hagihara coupling, during which C-C bonds are generated based on catalysis by these metals. Moreover, Pd2+ supporting s-BPy-PMO was found to act as an efficient heterogeneous catalyst for the Sonogashira-Hagihara coupling reaction and could be easily separated from the reaction solution by simple filtration and reused. In addition to this study using 4-Iodobenzaldehyde, there are many other studies that have used 4-Iodobenzaldehyde(cas: 15164-44-0Recommanded Product: 15164-44-0) was used in this study.

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Recommanded Product: 15164-44-0

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Gangadhar, Maram; Ramesh, Vankudoth; Prasad, Vadla Shiva; Adiyala, Praveen Reddy published an article in Journal of Organic Chemistry. The title of the article was 《Silver Ions Promoted Palladium-Catalyzed Inactive β-C(sp3)-H Bond Arylation in Batch and Continuous-Flow Conditions》.Computed Properties of C7H5IO The author mentioned the following in the article:

A palladium(II)-catalyzed protocol for inactive β-C(sp3)-H bond functionalization has been first accomplished. The reaction proceeds through five-membered carbocycles for the formation of C-C bonds via the Pd(II)/Pd(IV) cycle. This reaction was carried out with various aryl iodides RI (R = Ph, 9H-fluoren-2-yl, 3,5-di(trifluoromethyl)phenyl, etc.) and benzothiazoles/benzoxazoles/benzimidazoles I (X = S, O, NCH2Ph, etc.; R1 = H, 6-NO2, 5-NO2; R = H), which were well-tolerated in this reaction and successfully generated β-C(sp3)-H arylated products I. Further implementation of this batch protocol to continuous flow by utilizing a PTFE (polytetrafluoroethylene) capillary reactor enhanced the reaction efficiency and decreased the reaction time (18.4 min) as compared to batch conditions (8 h). Even on the gram scale, the process produced excellent yield with negligible diarylations. Functional group tolerance, a continuous-flow approach, and easy-to-handle reaction conditions make this inactive β-C(sp3)-H bond functionalization protocol very attractive. The experimental part of the paper was very detailed, including the reaction process of 4-Iodobenzaldehyde(cas: 15164-44-0Computed Properties of C7H5IO)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Computed Properties of C7H5IO

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Rerkrachaneekorn, Tanawat; Tankam, Theeranon; Sukwattanasinitt, Mongkol; Wacharasindhu, Sumrit published their research in Tetrahedron Letters in 2021. The article was titled 《NaI-mediated oxidative amidation of benzyl alcohols/aromatic aldehydes to benzamides via electrochemical reaction》.Related Products of 15164-44-0 The article contains the following contents:

In this research, authors have developed a mild electrochem. process for oxidative amidation of benzyl alcs./aromatic aldehydes with cyclic amines into the corresponding benzamides. This electroorg. synthetic method proceeds using NaI as a redox mediator under ambient temperature in undivided cell, providing more than 25 examples of amide products in moderate to good yields. The benefits of this reaction include one-pot synthesis, open air condition, proceed in aqueous media and no requirement of external conducting salt, base and oxidant. In the experiment, the researchers used many compounds, for example, 4-Iodobenzaldehyde(cas: 15164-44-0Related Products of 15164-44-0)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Related Products of 15164-44-0

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,Organic & Biomolecular Chemistry included an article by Pan, Yingying; Gong, Yuxin; Song, Yanhong; Tong, Weiqi; Gong, Hegui. Reference of 4-Iodobenzaldehyde. The article was titled 《Deoxygenative cross-electrophile coupling of benzyl chloroformates with aryl iodides》. The information in the text is summarized as follows:

This work describes Ni-catalyzed cross-electrophile coupling of benzyl chloroformate derivatives R1CH(R2)OC(O)Cl (R1 = C6H5, 4-FC6H4, 3-CH3C6H4, etc.; R2 = H, Me, butyl) with aryl iodides ArI (Ar = biphenyl-4-yl, naphthalen-1-yl, 3-oxo-2,3-dihydro-1H-inden-5-yl, 1-benzothiophen-5-yl, etc.) that generates a wide range of diaryl methane products R1CH(R2)Ar. The mild reaction conditions merit the C-O bond radical fragmentation of benzyl chloroformates via halide abstraction or a single electron reduction by a Ni catalyst. This work offers a new substrate type for cross-electrophile couplings. In the part of experimental materials, we found many familiar compounds, such as 4-Iodobenzaldehyde(cas: 15164-44-0Reference of 4-Iodobenzaldehyde)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Reference of 4-Iodobenzaldehyde

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Adenot, Aurelien; Anthore-Dalion, Lucile; Nicolas, Emmanuel; Berthet, Jean-Claude; Thuery, Pierre; Cantat, Thibault published their research in Chemistry – A European Journal in 2021. The article was titled 《A Copper(I)-Catalyzed Sulfonylative Hiyama Cross-Coupling》.Electric Literature of C7H5IO The article contains the following contents:

An air-tolerant Cu-catalyzed sulfonylative Hiyama cross-coupling reaction enabling the formation of diaryl sulfones is described. Starting from aryl silanes, DABSO and aryliodides, the reaction tolerates a large variety of polar functional groups (amines, ketones, esters, aldehydes). Control experiments coupled with DFT calculations shed light on the mechanism, characterized by the formation of a Cu(I)-sulfinate intermediate via fast insertion of a SO2 mol. The results came from multiple reactions, including the reaction of 4-Iodobenzaldehyde(cas: 15164-44-0Electric Literature of C7H5IO)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Electric Literature of C7H5IO

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com