Category: 15164-44-0

Cheng, Yaohang; Yu, Shijie; He, Yuhang; An, Guanghui; Li, Guangming; Yang, Zhenyu published an article in 2021. The article was titled 《C4-arylation and domino C4-arylation/3,2-carbonyl migration of indoles by tuning Pd catalytic modes: Pd(I)-Pd(II) catalysis vs. Pd(II) catalysis》, and you may find the article in Chemical Science.Application In Synthesis of 4-Iodobenzaldehyde The information in the text is summarized as follows:

Efficient C4-arylation and domino C4-arylation/3,2-carbonyl migration of indoles was developed. The former route enables C4-arylation in a highly efficient and mild manner and the latter route provides an alternative straightforward protocol for synthesis of C2/C4 disubstituted indoles. The mechanism studies imply that the different reaction pathways were tuned by the distinct acid additives, which led to either the Pd(I)-Pd(II) pathway or Pd(II) catalysis. In the experiment, the researchers used many compounds, for example, 4-Iodobenzaldehyde(cas: 15164-44-0Application In Synthesis of 4-Iodobenzaldehyde)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Application In Synthesis of 4-Iodobenzaldehyde

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Huang, Long-Ling; Lin, Peng-Peng; Li, Yu-Xin; Feng, Si-Xin; Tu, Fang-Hai; Yang, Shuang; Zhao, Gui-Yang; Huang, Zhi-Shu; Wang, Honggen; Li, Qingjiang published an article in Organic Letters. The title of the article was 《Oxidative Fluoroarylation of Benzylidenecyclopropanes with HF·Py and Aryl Iodides via Iodonio-[3,3]-Rearrangement》.Application In Synthesis of 4-Iodobenzaldehyde The author mentioned the following in the article:

Reported herein is an in situ-generated hypervalent iodine-incorporating fluoroarylation of benzylidenecyclopropanes using com. available HF·Py and aryl iodides as fluorine and aryl sources, resp. The reaction proceeds via regioselective 1,2-fluoroiodination of a double bond followed by an iodonio-[3,3]-rearrangement of the formed cyclopropyl-I(III) species. The protocol offers facile access to valuable monofluorinated 1,1-bis-benzyl-alkenes with mild reaction conditions and moderate to good yields. The synthetic utility of the products was demonstrated by further transformations. Preliminary mechanistic studies were conducted. The results came from multiple reactions, including the reaction of 4-Iodobenzaldehyde(cas: 15164-44-0Application In Synthesis of 4-Iodobenzaldehyde)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Application In Synthesis of 4-Iodobenzaldehyde

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Feng, Jianling; Wang, Qiang; Duan, Ruomeng; Li, Huadeng; Zheng, Ke; Wang, Xiaoxia; Xie, Guanqun published an article in 2022. The article was titled 《A facile electrosynthesis of N-acyl benzotriazoles from aldehydes and benzotriazole》, and you may find the article in Tetrahedron Letters.Category: iodides-buliding-blocks The information in the text is summarized as follows:

An electrochem. synthesis of N-acylbenzotriazoles I [R = Ph, 4-ClC6H4, 2-naphthyl, etc.] had been developed under mild conditions with good to excellent yields using aldehydes and benzotriazole as starting materials. In addition, a one-pot reaction of aldehyde, benzotriazole and phenol had been achieved affording phenolic esters II [R1 = Ph, 4-MeC6H4, 4-BrC6H4, etc.] in moderate yields under the combination of electricity-on/off conditions, where N-acyl benzotriazole acted as the benign acylating reagent. It was noteworthy the research provided environmental friendly syntheses in that no superstoichiometric hazardous chem. oxidants were required, corrosive/toxic reagents had been avoided and waste production had significantly been reduced. The key of the electrochem. synthesis involved the oxidation of benzotriazole-aldehyde adduct by phthalimido-N-oxy (PINO), which was generated by N-hydroxyphthalimide (NHPI) as a redox mediator. The experimental part of the paper was very detailed, including the reaction process of 4-Iodobenzaldehyde(cas: 15164-44-0Category: iodides-buliding-blocks)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Category: iodides-buliding-blocks

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Maiti, Sudip; Li, Yingzi; Sasmal, Sheuli; Guin, Srimanta; Bhattacharya, Trisha; Lahiri, Goutam Kumar; Paton, Robert S.; Maiti, Debabrata published an article in Nature Communications. The title of the article was 《Expanding chemical space by para-C-H arylation of arenes》.Electric Literature of C7H5IO The author mentioned the following in the article:

A robust catalytic system that displayed unique efficacy toward para-arylation of highly functionalized substrates such as drug entities, giving access to structurally diversified biaryl scaffolds, e.g., I was developed. This diversification process provided access to an expanded chem. space for further exploration in drug discovery. Further, the applicability of the transformation was realized through the synthesis of drug mols. bearing a biphenyl fragment. Computational and exptl. mechanistic studies further provided insight into the catalytic cycle operative in this versatile C-H arylation protocol. In the experiment, the researchers used many compounds, for example, 4-Iodobenzaldehyde(cas: 15164-44-0Electric Literature of C7H5IO)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Electric Literature of C7H5IO

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Nallagonda, Rajender; Musaev, Djamaladdin G.; Karimov, Rashad R. published an article in ACS Catalysis. The title of the article was 《Light-Promoted Dearomative Cross-Coupling of Heteroarenium Salts and Aryl Iodides via Nickel Catalysis》.Safety of 4-Iodobenzaldehyde The author mentioned the following in the article:

Herein, the coupling of aryl iodides, e.g., Ph iodide with pyridinium and related heteroarenium salts, e.g., I catalyzed by Ni/bpp and an Ir photocatalyst using Zn as a terminal reductant was reported. This methodol. tolerates a wide range of functional groups and allows the coupling of aryl and heteroaryl iodides, thus significantly expanding the scope of nitrogen heterocycle scaffolds, e.g., II that could be prepared through dearomatization of heteroarenes. The reaction products have been further functionalized to prepare various nitrogen heterocycles. Initial mechanistic studies indicate that the reaction described herein goes through a unique mechanism involving dimers of dihydroheteroarenes. In the experiment, the researchers used many compounds, for example, 4-Iodobenzaldehyde(cas: 15164-44-0Safety of 4-Iodobenzaldehyde)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Safety of 4-Iodobenzaldehyde

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Palladium nanoparticles encapsuled in MOF: An efficient dual-functional catalyst to produce benzylmalononitrile derivatives by one-pot reaction》 was written by Zhang, Yu-Yang; Zhou, Mei-Li; Bao, Yan-Sai; Yang, Ming; Cui, Yong-He; Liu, Da-Liang; Wu, Qiong; Liu, Lin; Han, Zheng-Bo. HPLC of Formula: 15164-44-0This research focused onzeolite type metal organic framework encapsulated palladium nanocatalyst preparation; benzylmalononitrile preparation; alkyne malononitrile halobenzaldehyde Sonogashira Knoevenagel palladium nanocatalyst; alkene malononitrile halobenzaldehyde Heck Knoevenagel palladium nanocatalyst. The article conveys some information:

Herein, Pd nanoparticles were loaded on a zeolite-type metal-organic framework (MOF) (MIL-101(Cr)-NH2) via post-synthetic impregnation approach to form composites Pd@MIL-101(Cr)-NH2. In addition, the obtained dual-functional Pd@MIL-101(Cr)-NH2 showed great catalytic performance (>99% yields) in the one-pot Sonogashira-Knoevenagel and Heck-Knoevenagel reactions. Furthermore, all characterization methods showed that catalyst with Pd-Bronsted base had high stability to avoid metal agglomeration, leaching, and still maintained high activity after 6 cycles under the same circumstances. These reactions had potential significance for the production of benzylmalononitrile derivatives with high economic benefits. In the experiment, the researchers used many compounds, for example, 4-Iodobenzaldehyde(cas: 15164-44-0HPLC of Formula: 15164-44-0)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.HPLC of Formula: 15164-44-0

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Pd-Catalyzed Boroperfluoroalkylation of Alkynes Opens a Route to One-Pot Reductive Carboperfluoroalkylation of Alkynes with Perfluoroalkyl and Aryl Iodides》 were Domanski, Sylwester; Gatlik, Beata; Chaladaj, Wojciech. And the article was published in Organic Letters in 2019. Name: 4-Iodobenzaldehyde The author mentioned the following in the article:

A three-component tandem Pd-catalyzed perfluoroalkylative borylation of terminal and internal alkynes is presented. On the basis of this methodol., the first reductive dicarbofunctionalization of alkynes with two electrophiles (perfluoroalkyl and aryl iodides) through a temperature-controlled sequence of iodoperfluoroalkylation-borylation coupling is developed. This regio- and stereoselective process is easily controllable by a temperature program, providing access to fluoroalkyl-substituted vinyl iodides, vinyl boronates, or olefins from the very same complex reaction mixture (four substrates, catalysts, base, and additives). After reading the article, we found that the author used 4-Iodobenzaldehyde(cas: 15164-44-0Name: 4-Iodobenzaldehyde)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Name: 4-Iodobenzaldehyde

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Zhang, Jianyu; Alam, Parvej; Zhang, Siwei; Shen, Hanchen; Hu, Lianrui; Sung, Herman H. Y.; Williams, Ian D.; Sun, Jianwei; Lam, Jacky W. Y.; Zhang, Haoke; Tang, Ben Zhong published an article in Nature Communications. The title of the article was 《Secondary through-space interactions facilitated single-molecule white-light emission from clusteroluminogens》.Recommanded Product: 4-Iodobenzaldehyde The author mentioned the following in the article:

Clusteroluminogens refer to some non-conjugated mols. that show visible light and unique electronic properties with through-space interactions due to the formation of aggregates. Although mature and systematic theories of mol. photophysics have been developed to study conventional conjugated chromophores, it is still challenging to endow clusteroluminogens with designed photophys. properties by manipulating through-space interactions. Herein, three clusteroluminogens with non-conjugated donor-acceptor structures and different halide substituents are designed and synthesized. These compounds show multiple emissions and even single-mol. white-light emission in the crystalline state. The intensity ratio of these emissions is easily manipulated by changing the halide atom and excitation wavelength. Exptl. and theor. results successfully disclose the electronic nature of these multiple emissions: through-space conjugation for short-wavelength fluorescence, through-space charge transfer based on secondary through-space interactions for long-wavelength fluorescence, and room-temperature phosphorescence. The introduction of secondary through-space interactions to clusteroluminogens not only enriches their varieties of photophys. properties but also inspires the establishment of novel aggregate photophysics for clusteroluminescence. The results came from multiple reactions, including the reaction of 4-Iodobenzaldehyde(cas: 15164-44-0Recommanded Product: 4-Iodobenzaldehyde)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Recommanded Product: 4-Iodobenzaldehyde

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《A proficient microwave synthesis with structure elucidation and the exploitation of the biological behavior of the newly halogenated 3-amino-1H-benzo[f]chromene molecules, targeting dual inhibition of topoisomerase II and microtubules》 was published in Bioorganic Chemistry in 2020. These research results belong to Fouda, Ahmed M.; Okasha, Rawda M.; Alblewi, Fawzia F.; Mora, Ahmed; Afifi, Tarek H.; El-Agrody, Ahmed M.. COA of Formula: C7H5IO The article mentions the following:

A series of β-enamionitriles, linked to the 8-bromo-1H-benzo[f]chromene moieties I (Ar = 2-ClC6H4, 4-IC6H4, 2,6-F2C6H3, etc.), was designed and synthesized under microwave irradiation conditions. Furthermore, the antiproliferative properties were evaluated against the human cancer cell lines MCF-7, HCT-116, and HepG-2 in comparison to the pos. controls Vinblastine and Doxorubicin, employing the viability assay. The obtained results confirmed that most of the tested mols. revealed strong and selective cytotoxic activities against the three cancer cell lines. The most potent cytotoxic compounds I (Ar = 2-ClC6H4, 4-ClC6H4, 4-BrC6H4, 2,3-Cl2C6H3, 2,5-Cl2C6H3) were elected for further examination, such as cell cycle anal., apoptosis assay, Caspase production, and DNA fragmentation. This study also revealed that the desired compounds stimulate cell cycle arrest at the G2/M phases, increase the production of Caspases 3, 8, and 9, and finally cause intrinsic and extrinsic apoptotic cell death. Moreover, these compounds suppress the action of topoisomerase II enzyme and also disrupt the microtubule functions. The SAR study of the synthesized compounds verified that the substitution on the Ph ring of the 1H-benzo[f]chromene nucleus, accompanied with the presence of the bromine atom at the 8-position, increases the ability of these mols. against different cell lines. After reading the article, we found that the author used 4-Iodobenzaldehyde(cas: 15164-44-0COA of Formula: C7H5IO)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.COA of Formula: C7H5IO

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Zhang, Min; Fu, Zhangyi; Luo, Anping; Pu, Xingwen; Wang, Menglei; Huang, Ying; Yang, Yudong; You, Jingsong published an article in 2021. The article was titled 《Palladium-catalyzed C8-H arylation and annulation of 1-naphthalene carboxylic acid derivatives with aryl iodides》, and you may find the article in Organic Chemistry Frontiers.Recommanded Product: 15164-44-0 The information in the text is summarized as follows:

Palladium-catalyzed C8-H arylation of 1-naphthoic acids with aryl iodides in a low reactant molar ratio via an electrophilic aromatic substitution (SEAr) process. In addition, a C8-H annulation protocol was developed to rapidly assembled to benzanthrones by simply switching the solvent to 1,1,1,3,3,3-hexafluoropropan-2-ol. In the experiment, the researchers used 4-Iodobenzaldehyde(cas: 15164-44-0Recommanded Product: 15164-44-0)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Recommanded Product: 15164-44-0

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com