Related Products of 1483-73-4, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 1483-73-4 name is Diphenyliodonium bromide, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
EXAMPLE 34 Preparation of trans-3-phenyl-4-(4-phenoxyphenyl)-2-piperidone 34 6.2 g (0.023 mol) of trans-4-(4-hydroxyphenyl)-3-phenyl-2-piperidone 27, 8.6 g (0.023 mol) of diphenyliodonium bromide and a solution of 0.94 g of sodium hydroxide in 170 cm3 of double-distilled water are brought to reflux with stirring for 24 hours. The mixture is cooled and extracted with methylene chloride. The organic phase is washed successively with 5% strength sodium hydroxide solution and with water to neutrality, and dried over anhydrous sodium sulfate. After filtration and evaporation, 6 g of a solid are obtained and this is recrystallized in methanol. 5.3 g (66%) of pure 34 are obtained, m.p. 157-159 C. Analysis: C23 H21 NO2: IR(KBr): nuN–H at 3,200 cm-1, moderate, nuC=O at 1,660 cm-1, strong, nuC–O–C at 1,240 cm-1, strong.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, Diphenyliodonium bromide, and friends who are interested can also refer to it.
Reference:
Patent; Laboratoires Hoechst S.A.; US4785007; (1988); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com