Category: 134322-01-3

Lin, Shizhuo published the artcileLayered Double Hydroxides as Reusable Catalysts for Cyclocondensation of Amidines and Aminoalcohols: Access to Multi-functionalized Oxazolines, Computed Properties of 134322-01-3, the publication is Journal of Organic Chemistry (2022), 87(2), 1366-1376, database is CAplus and MEDLINE.

An efficient catalytic protocol based on reusable MgAl-layered double hydroxides has been developed for the synthesis of multi-functionalized oxazolines via the cyclocondensation of amidines and aminoalcs. The developed method has a broad substrate scope and excellent functional group tolerance and uses a reusable catalyst. The catalyst can be conveniently recycled by filtration and reused for at least five times without obvious deactivation. Addnl., the selective ortho C-H silylation of oxazolines was performed using Ru(II) as the catalyst and tri-Et silane as the silylating reagent, which proved to be a convenient and practical method for the synthesis of versatile organosilyl-functionalized oxazolines with advantageous biol. and phys. properties.

Journal of Organic Chemistry published new progress about 134322-01-3. 134322-01-3 belongs to iodides-buliding-blocks, auxiliary class Salt,Iodide,Amine,Amidine,Benzene, name is 4-Iodobenzimidamide hydrochloride, and the molecular formula is C7H8ClIN2, Computed Properties of 134322-01-3.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Sun, Li-Wen published the artcileTransition-metal-free hydroamination/defluorination/cyclization of perfluoroalkyl alkynes with amidines, Related Products of iodides-buliding-blocks, the publication is Organic Chemistry Frontiers (2022), 9(1), 109-116, database is CAplus.

An efficient defluorinative net-[3 + 3]-cyclization strategy for the construction of perfluoroalkyl-substituted pyrimidine derivatives by using a series of perfluoroalkyl alkynes and amidines as starting materials was developed. The present reaction proceeded successfully under transition-metal-free conditions to form two new C-N bonds and a new heterocyclic ring through a sequence of hydroamination, defluorination, and annulation. The desired pyrimidines could be obtained with good functional group tolerance and moderate to good yields. Moreover, the distinctive fluorine effects of perfluoroalkyl substituents are vital for tuning the reactivity of alkynes for the anticipated defluorinative annulation. The pendant π system would lower associated bond dissociation energy significantly compared to that of a nonactivated C(sp3)-F bond.

Organic Chemistry Frontiers published new progress about 134322-01-3. 134322-01-3 belongs to iodides-buliding-blocks, auxiliary class Salt,Iodide,Amine,Amidine,Benzene, name is 4-Iodobenzimidamide hydrochloride, and the molecular formula is C10H14O, Related Products of iodides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Hudson, Christine M. published the artcileSynthesis and mesomorphic properties of some disubstituted unsymmetrical phenyl-1,2,4,5-tetrazines, Quality Control of 134322-01-3, the publication is Liquid Crystals (1995), 19(6), 871-81, database is CAplus.

The synthesis of unsym. phenyl-1,2,4,5-tetrazines containing a cyano group either on the Ph ring (1a) or the tetrazine ring (11a, 11b) was accomplished by the introduction of the cyano group after formation of the tetrazine ring. The mesomorphic, solubility and absorption properties of these tetrazines and alkoxy tetrazines (12a–d) were studied. The compounds containing the cyano group on the tetrazine ring showed smectic A phases while nematic phases were observed in some of the alkoxy tetrazines.

Liquid Crystals published new progress about 134322-01-3. 134322-01-3 belongs to iodides-buliding-blocks, auxiliary class Salt,Iodide,Amine,Amidine,Benzene, name is 4-Iodobenzimidamide hydrochloride, and the molecular formula is C7H8ClIN2, Quality Control of 134322-01-3.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Reddy, M. L. Chenna published the artcileSynthesis of New Sulfoximine-Tethered Alkynones and Further Extension towards Metal-Free Synthesis of Pyrimidines, Amino Pyrimidines, Pyrazoles and Isoxazoles, Category: iodides-buliding-blocks, the publication is ChemistrySelect (2019), 4(33), 9573-9577, database is CAplus.

A metal-free and divergent synthetic method has been successfully developed for the synthesis of sulfoximine-tethered pyrimidines, aminopyrimidines, pyrazoles and isoxazoles. Two key sulfoximine tethered alkynone intermediates ((tert-butyldiphenylsilyl)imino)(2-oxo-4-phenylbut-3-yn-1-yl)(phenyl)-λ6-sulfanone and ((tert-butyldiphenylsilyl)imino)(2-oxopent-3-yn-1-yl)(phenyl)-λ6-sulfanone were reported for the first time and were used as the common building blocks to construct these heterocycles. Good functional group tolerability was observed and the products were isolated in excellent yields.

ChemistrySelect published new progress about 134322-01-3. 134322-01-3 belongs to iodides-buliding-blocks, auxiliary class Salt,Iodide,Amine,Amidine,Benzene, name is 4-Iodobenzimidamide hydrochloride, and the molecular formula is C7H8ClIN2, Category: iodides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Inturi, Surendra Babu published the artcileI₂ mediated one-pot synthesis of 1,2,4-triazoles from amidines and imidates, Related Products of iodides-buliding-blocks, the publication is Tetrahedron Letters (2016), 57(21), 2227-2230, database is CAplus.

A one-pot facile synthesis of 3,5-disubstituted-1H-1,2,4-triazole derivatives using I₂/Cs₂CO₃ was described. The method involves readily available inexpensive reagents and is applicable to a wide range of substrates. The transformation involves one-pot sequential C-N and N-N bond forming reactions with high product yields and selectivity, and offers a new and useful strategy for the synthesis of 3,5-disubstituted-1H-1,2,4-triazole derivatives

Tetrahedron Letters published new progress about 134322-01-3. 134322-01-3 belongs to iodides-buliding-blocks, auxiliary class Salt,Iodide,Amine,Amidine,Benzene, name is 4-Iodobenzimidamide hydrochloride, and the molecular formula is C7H8ClIN2, Related Products of iodides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com