Category: 1287221-36-6

On July 15, 2022, Nguyen, Viet D.; Trevino, Ramon; Greco, Samuel G.; Arman, Hadi D.; Larionov, Oleg V. published an article.HPLC of Formula: 1287221-36-6 The title of the article was Tricomponent Decarboxysulfonylative Cross-coupling Facilitates Direct Construction of Aryl Sulfones and Reveals a Mechanistic Dualism in the Acridine/Copper Photocatalytic System. And the article contained the following:

A dual catalytic process that enabled the previously inaccessible, broad-scope, direct conversion of carboxylic acids to aromatic sulfones-centrally important carbonyl group bioisosteric replacements and synthetic intermediates-by a tricomponent decarboxysulfonylative cross-coupling with aryl halides was reported. Detailed mechanistic and computational studies revealed the roles of the copper catalysts, bases and halide anions in channeling the acridine/copper system via a distinct dual catalytic manifold. In contrast to the halide-free decarboxylative conjugate addition that involved cooperative dual catalysis via low-valent copper species, the halide counteranions divert the decarboxysulfonylative cross-coupling with aryl halides through a two-phase, orthogonal relay catalytic manifold, comprising a kinetically coupled (via antithetical inhibitory and activating roles of the base in the two catalytic cycles), mechanistically discrete sequence of a photoinduced, acridine-catalyzed decarboxylative process and a thermal copper-catalyzed arylative coupling. The study underscores the importance of non-innocent roles of counteranions and key redox steps at the interface of catalytic cycles for enabling previously inaccessible dual catalytic transformations. The experimental process involved the reaction of 4-Iodophenylboronic acid MIDA ester(cas: 1287221-36-6).HPLC of Formula: 1287221-36-6

The Article related to carboxylic acid aryl halide potassium metabisulfite acridine copper catalyst, aromatic halide carboxylic acid dabso acridine copper catalyst, aryl sulfone preparation tricomponent decarboxysulfonylative cross coupling reaction and other aspects.HPLC of Formula: 1287221-36-6

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

On July 15, 2022, Nguyen, Viet D.; Trevino, Ramon; Greco, Samuel G.; Arman, Hadi D.; Larionov, Oleg V. published an article.HPLC of Formula: 1287221-36-6 The title of the article was Tricomponent Decarboxysulfonylative Cross-coupling Facilitates Direct Construction of Aryl Sulfones and Reveals a Mechanistic Dualism in the Acridine/Copper Photocatalytic System. And the article contained the following:

A dual catalytic process that enabled the previously inaccessible, broad-scope, direct conversion of carboxylic acids to aromatic sulfones-centrally important carbonyl group bioisosteric replacements and synthetic intermediates-by a tricomponent decarboxysulfonylative cross-coupling with aryl halides was reported. Detailed mechanistic and computational studies revealed the roles of the copper catalysts, bases and halide anions in channeling the acridine/copper system via a distinct dual catalytic manifold. In contrast to the halide-free decarboxylative conjugate addition that involved cooperative dual catalysis via low-valent copper species, the halide counteranions divert the decarboxysulfonylative cross-coupling with aryl halides through a two-phase, orthogonal relay catalytic manifold, comprising a kinetically coupled (via antithetical inhibitory and activating roles of the base in the two catalytic cycles), mechanistically discrete sequence of a photoinduced, acridine-catalyzed decarboxylative process and a thermal copper-catalyzed arylative coupling. The study underscores the importance of non-innocent roles of counteranions and key redox steps at the interface of catalytic cycles for enabling previously inaccessible dual catalytic transformations. The experimental process involved the reaction of 4-Iodophenylboronic acid MIDA ester(cas: 1287221-36-6).HPLC of Formula: 1287221-36-6

The Article related to carboxylic acid aryl halide potassium metabisulfite acridine copper catalyst, aromatic halide carboxylic acid dabso acridine copper catalyst, aryl sulfone preparation tricomponent decarboxysulfonylative cross coupling reaction and other aspects.HPLC of Formula: 1287221-36-6

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Fyfe, James W. B.; Valverde, Elena; Seath, Ciaran P.; Kennedy, Alan R.; Redmond, Joanna M.; Anderson, Niall A.; Watson, Allan J. B. published an article in 2015, the title of the article was Speciation control during Suzuki-Miyaura cross-coupling of haloaryl and haloalkenyl MIDA boronic esters.Application of 1287221-36-6 And the article contains the following content:

Effects of aryl halide, water, base, reaction temperature, catalyst precursor and ligand on chemoselectivity of Suzuki coupling of PhBpin with 4-HalC6H4BMIDA, producing 4-PhC6H4Bpin with up to 92% selectivity, were evaluated. Boronic acid solution speciation can be controlled during the Suzuki-Miyaura cross-coupling of haloaryl N-methyliminodiacetic acid (MIDA) boronic esters to enable the formal homologation of boronic acid derivatives The reaction is contingent upon control of the basic biphase and is thermodynamically driven: temperature control provides highly chemoselective access to either BMIDA adducts at room temperature or boronic acid pinacol ester (BPin) products at elevated temperature Control experiments and solubility analyses have provided some insight into the mechanistic operation of the formal homologation process. The experimental process involved the reaction of 4-Iodophenylboronic acid MIDA ester(cas: 1287221-36-6).Application of 1287221-36-6

The Article related to suzuki coupling chemoselectivity pinacol mida boronate preparation biaryl, aryl halide solvent base temperature effect chemoselectivity suzuki coupling, homologation boronate arylene insertion chemoselective suzuki coupling pinacol mida, boron, chemoselectivity, cross-coupling, palladium, speciation and other aspects.Application of 1287221-36-6

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com