Reference of 101335-11-9, The chemical industry reduces the impact on the environment during synthesis 101335-11-9, name is 2-Chloro-4-fluoro-1-iodobenzene, I believe this compound will play a more active role in future production and life.
Sodium methanethiolate (5g) was added to a solution of 4-fluoro-2-chloro-iodobenzene (18.3g) and stirred for 20h. The mixture was poured into water, extracted with ether, washed with brine, dried (MgS04) and evaporated. Yield 18. 5g. 1H NMR DMSO-d6: 8 7.81 (d, 1H), 7.43 (dd, 1H), 6.98 (dd, 1H), 3.32 (s, 3H)
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Chloro-4-fluoro-1-iodobenzene, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; ASTRAZENECA AB; WO2004/89885; (2004); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com