Isopropanol and potassium tert-butoxide promoted intramolecular direct sp2 C-H functionalization: an expedient synthesis of 1,2,3-triazole annulated chromens and quinolones was written by Mondal, Biplab;Roy, Brindaban. And the article was included in Tetrahedron Letters in 2015.Electric Literature of C6H4BrIO This article mentions the following:
A series of 1,2,3-triazole annulated chromen I (R1 = H, 8-Me, 8-t-Bu, 8-Br, 6,8-di-Cl, 8-Cl, 8-CO2Et; R2 = Bn, 2-NO2Bn, 1-octyl, 1-heptyl), and quinolone derivatives II (R3 = Me, Et, n-Bu) have been synthesized by means of direct sp2 C-H functionalization in the presence of iso-propanol and potassium tert-butoxide. The reaction proceeds through homolytic aromatic substitution (HAS). This efficient as well as simple C-H functionalization methodol. offers a straightforward route to 1,2,3-triazole annulated oxygen and nitrogen heterocycles. In the experiment, the researchers used many compounds, for example, 4-Bromo-2-iodophenol (cas: 207115-22-8Electric Literature of C6H4BrIO).
4-Bromo-2-iodophenol (cas: 207115-22-8) belongs to iodide derivatives. Organic iodides are widely used in organic synthesis. Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I.Electric Literature of C6H4BrIO
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com