BODIPY-Labeled Cyclobutanes by Secondary C(sp3)-H Arylations for Live-Cell Imaging was written by Virelli, Matteo;Wang, Wei;Kuniyil, Rositha;Wu, Jun;Zanoni, Giuseppe;Fernandez, Antonio;Scott, Jamie;Vendrell, Marc;Ackermann, Lutz. And the article was included in Chemistry – A European Journal in 2019.Application of 5460-32-2 This article mentions the following:
Arylated cyclobutanes were accessed by a versatile palladium-catalyzed secondary C(sp3)-H activation, exploiting chelation assistance by modular triazoles. The C-H arylation led to cyclobutane natural product derivatives in a highly regioselective fashion, setting the stage for the easy access to novel fluorogenic boron-dipyrrin (BODIPY)-labeled probes for live-cell imaging. In the experiment, the researchers used many compounds, for example, 4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2Application of 5460-32-2).
4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2) belongs to iodide derivatives. Organic iodides are widely used in organic synthesis. Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Application of 5460-32-2
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com