Christie, G. H. et al. published their research in Journal of the Chemical Society, Transactions in 1923 | CAS: 123278-03-5

3-Chloro-2-iodobenzoic acid (cas: 123278-03-5) belongs to iodide derivatives. Iodide-containing intermediates are common in organic synthesis, because of the easy formation and cleavage of the C–I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Recommanded Product: 123278-03-5

Molecular configuration of polynuclear aromatic compounds. IV. 6,6′-Dichlorodiphenic acid; its synthesis and resolution into optically active components was written by Christie, G. H.;James, C. W.;Kenner, James. And the article was included in Journal of the Chemical Society, Transactions in 1923.Recommanded Product: 123278-03-5 This article mentions the following:

2-Iodoaceto-m-toluidide is oxidized by KMnO4 in boiling H2O containing MgSO4 to 2-iodo-3-acetylaminobenzoic acid, m. 199°. Hydrolysis with concentrated HCl gives the HCl salt of 2-iodo-3-aminobenzoic acid, m. 262-3°. 3-Chloro-2-iodobenzoic acid, m. 137-8°; Me ester, b28 182°; Et ester, b15 175°. The Me ester and Cu powder, heated 1 hr. at 230-40°, give 6,6′-dichlorodiphenic acid, m. 288°, as the Me ester, m. 156°. Et ester, m. 103-4°. Repeated fractional crystallization of the mixture of salts from 2 g. acid and 6 g. hydrated brucine gave 2.3 g. of brucine 1-6,6′-dichlorodiphenate, C60H60O12N4Cl2.3H2O, m. 235°; and is the less soluble of the 2 salts. [α]D15 1.97 (CHCl3, c 1.23%). The d-salt, obtained in a yield of 1.35 g., m. 163° (decomposition), is the more soluble and has [α]D15 -58.62° (CHCl3, c 1.16%). This salt crystallines with 1.5 H2O. d-6,6′-Dichlorodiphenic acid, m. 259°. A 0.69% solution of the Na salt showed [α]D15 -20.18°. The l-acid m. 259°; a 1.01% aqueous solution of the Na salt showed [α]D15 21.43°. These results confirm the correctness of the assumption that the cause of the stereoisomerism of the various nitrodiphenic acids previously investigated is not to be sought in any peculiar property of the NO2 group. In the experiment, the researchers used many compounds, for example, 3-Chloro-2-iodobenzoic acid (cas: 123278-03-5Recommanded Product: 123278-03-5).

3-Chloro-2-iodobenzoic acid (cas: 123278-03-5) belongs to iodide derivatives. Iodide-containing intermediates are common in organic synthesis, because of the easy formation and cleavage of the C–I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Recommanded Product: 123278-03-5

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com