Arylselenyl Radical-Mediated Cyclization of N-(2-Alkynyl)anilines: Access to 3-Selenylquinolines was written by Zhu, Changlei;Nurko, Max;Day, Cynthia S.;Lukesh, John C. III. And the article was included in Journal of Organic Chemistry in 2022.HPLC of Formula: 5460-32-2 This article mentions the following:
An efficient and novel approach to accessing 3-selenylquinolines I [R1 = H, 6-I, 8-Me, etc.; R2 = n-Bu, Ph, 3-thienyl, etc.; R3 = Ph, 2-MeC6H4, 3-thienyl, etc.] from diaryl diselenides and acyclic, selenium-free substrates was described. Preliminary mechanistic studies indicated that the combination of CuCl2 and air afforded an appropriate environment for producing arylselenyl radicals that initiated the cascade cyclization of N-(2-alkynyl)anilines, forming key Se-C and C-C bonds in a single step. Using this chem., a wide variety of 3-selenylquinolines were produced in moderate to excellent yield under mild conditions, highlighting the versatility and usefulness of this new method. In the experiment, the researchers used many compounds, for example, 4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2HPLC of Formula: 5460-32-2).
4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2) belongs to iodide derivatives. Organoiodine compounds occur widely in organic chemistry, but are relatively rare in nature. Polyiodoorganic compounds are sometimes employed as X-ray contrast agents, in fluoroscopy, a type of medical imaging. This application exploits the X-ray absorbing ability of the heavy iodine nucleus.HPLC of Formula: 5460-32-2
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com