First total synthesis of fungerin, an antifungal alkaloid from Fusarium sp. was written by Benhida, Rachid;Lezama, Ruth;Fourrey, Jean-Louis. And the article was included in Tetrahedron Letters in 1998.Electric Literature of C3H2I2N2 This article mentions the following:
The first total synthesis of fungerin, a new antifungal alkaloid, is described. Starting from a 4,5-diiodoimidazole derivative, the procedure involves regioselective prenylation and Heck type reaction steps to give fungerin in high yield. In the experiment, the researchers used many compounds, for example, 4,5-Diiodo-1H-imidazole (cas: 15813-09-9Electric Literature of C3H2I2N2).
4,5-Diiodo-1H-imidazole (cas: 15813-09-9) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. A typical method for synthesis of aromatic iodides is diazotization of primary aromatic amines followed by treatment of potassium iodide. Aliphatic alcohols are converted to alkyl iodides by treating with hydrogen iodide.Electric Literature of C3H2I2N2
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com