Copper-Catalyzed Diaryl Ether Formation from (Hetero)aryl Halides at Low Catalytic Loadings was written by Zhai, Yuntong;Chen, Xiaofei;Zhou, Wei;Fan, Mengyang;Lai, Yisheng;Ma, Dawei. And the article was included in Journal of Organic Chemistry in 2017.Recommanded Product: 3-Iodobenzo[b]thiophene This article mentions the following:
Diaryl formation is achieved by coupling phenols and (hetero)aryl halides under the catalysis of CuI/N,N’-bis(2-phenylphenyl) oxalamide (BPPO) or CuI/N-(2-phenylphenyl)-N’-benzyl oxalamide (PPBO) at 90 °C using DMF or MeCN as the solvent. Only 0.2-2 mol % CuI and ligand are required for complete conversion, which represents the lowest catalytic loadings for a general Cu/ligand-catalyzed diaryl ether formation. In the experiment, the researchers used many compounds, for example, 3-Iodobenzo[b]thiophene (cas: 36748-88-6Recommanded Product: 3-Iodobenzo[b]thiophene).
3-Iodobenzo[b]thiophene (cas: 36748-88-6) belongs to iodide derivatives. Iodide-containing intermediates are common in organic synthesis, because of the easy formation and cleavage of the C–I bond. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I. This periodic order also follows the atomic radius of halogens and the length of the carbon-halogen bond.Recommanded Product: 3-Iodobenzo[b]thiophene
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com