Microwave-assisted efficient synthesis of 2-arylbenzo[b]furans and 2-ferrocenylbenzo[b]furans from readily prepared propargylic alcohols and o-iodophenols was written by Wu, Liansheng;Shi, Xiaokang;Xu, Xiaoyun;Liang, Fen;Huang, Guosheng. And the article was included in Journal of Chemical Sciences (Bangalore, India) in 2011.Computed Properties of C6H4BrIO This article mentions the following:
A simple, efficient, and expeditious method for the synthesis of 2-aryl- and 2-ferrocenylbenzofurans from readily prepared propargylic alcs. and 2-iodophenols using SiO2 and PdCl2(PPh3)2 (2 mol%)/CuI (2 mol%) catalyst by microwave-promoted Sonogashira coupling/cyclization was developed. The methodol. gives good to excellent yields. In addition, this method can also be completed in one-pot with PhI, 2-methyl-3-butyn-2-ol, and 2-iodo-4-methylphenol as reactants. In the experiment, the researchers used many compounds, for example, 4-Bromo-2-iodophenol (cas: 207115-22-8Computed Properties of C6H4BrIO).
4-Bromo-2-iodophenol (cas: 207115-22-8) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Computed Properties of C6H4BrIO
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com