Electrochemical Fluorination of Vinyl Boronates through Donor-Stabilized Vinyl Carbocation Intermediates was written by Wigman, Benjamin;Lee, Woojin;Wei, Wenjing;Houk, Kendall N.;Nelson, Hosea M.. And the article was included in Angewandte Chemie, International Edition in 2022.Recommanded Product: 5460-32-2 This article mentions the following:
The electrochem. generation of vinyl carbocations RC(F)=C(R1)R2 (R = 4-methoxyphenyl, thiophen-2-yl, 2,2-dimethyl-2H-1,3-benzodioxol-5-yl, etc.; R1 = R2 = n-Bu, 4-methoxyphenyl; R1R2 = -(CH2)4-, -(CH2)5-) from alkenyl boronic esters and boronates RC(Bpin)=C(R1)R2 is reported. Using easy-to-handle nucleophilic fluoride reagents, these intermediates are trapped to form fully substituted vinyl fluorides. Mechanistic studies support the formation of dicoordinated carbocations through sequential single-electron oxidation events. Notably, this electrochem. fluorination features fast reaction times and Lewis acid-free conditions. This transformation provides a complementary method to access vinyl fluorides with simple fluoride salts such as TBAF. In the experiment, the researchers used many compounds, for example, 4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2Recommanded Product: 5460-32-2).
4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. Polyiodoorganic compounds are sometimes employed as X-ray contrast agents, in fluoroscopy, a type of medical imaging. This application exploits the X-ray absorbing ability of the heavy iodine nucleus.Recommanded Product: 5460-32-2
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com