Use of Koser’s reagent for the iodination of the rings of polyalkylbenzenes was written by Bovonsombat, Pakorn;Angara, Geetha J.;McNelis, Edward. And the article was included in Synlett in 1992.Formula: C10H12I2 This article mentions the following:
[Hydroxy(tosyloxy)iodo]benzene (Koser’s reagent) was used in catalytic quantities with N-iodosuccinimide and in stoichiometric quantities with iodine to iodinate the rings of polyalkylbenzenes (4 examples). In the experiment, the researchers used many compounds, for example, 1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1Formula: C10H12I2).
1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1) belongs to iodide derivatives. Iodide-containing intermediates are common in organic synthesis, because of the easy formation and cleavage of the C–I bond. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Formula: C10H12I2
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com