Wang, Shan published the artcileEnantioselective access to chiral aliphatic amines and alcohols via Ni-catalyzed hydroalkylations, Quality Control of 638-45-9, the publication is Nature Communications (2021), 12(1), 2771, database is CAplus and MEDLINE.
A nickel-catalyzed enantioselective hydroalkylation of acyl enamines R1C(O)N(R2)CH=CH2 (R1 = C6H5, 1-naphthyl, 2-furyl, etc.; R2 = H, Me) and enol esters R3C(O)OCH=CH2R4 (R3 = C6H5, 4-CH3OC6H4, 2-naphthyl; R4 = H, C4H9, C6H13, (CH2)4Cl) with alkyl halides R5I [R5 = 2-phenylethyl, 3-(thiophen-2-yl)propyl, 3-(9H-carbazol-9-yl)propyl, etc.] to afford enantioenriched α-branched aliphatic acyl amines (R)-R1C(O)N(R2)CH(R5)Me and esters R3C(O)OCH(R5)CH2R4 in good yields with excellent levels of enantioselectivity has been described. The operationally simple protocol provides a straightforward access to chiral secondary alkyl-substituted amine and secondary alkyl-substituted alc. derivatives from simple starting materials with great functional group tolerance.
Nature Communications published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C17H16O2, Quality Control of 638-45-9.
Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com