Huang, Zhuo-Bin published the artcileSelective C-H dithiocarbamation of arenes and antifungal activity evaluation, Application of 4-Iodo-1-methyl-1H-pyrazol-5-amine, the publication is Organic & Biomolecular Chemistry (2020), 18(7), 1369-1376, database is CAplus and MEDLINE.
This paper discloses a transition metal-free selective C-H dithiocarbamation of drug skeletons using disulfiram (DSF) in the presence of KI/K2S2O8 in DMF/H2O. Drug skeletons, including 5-aminopyrazoles, indoles, pyrroloquinoline, and Julolidine, underwent C-H dithiocarbamation smoothly to afford a variety of drug-like mols. in moderate to good yields. It was found that the in situ formed 5-aminopyrazole iodide is the key intermediate for the dithiocarbamation. Bioassay results show that some of these N-heterocyclic dithiocarbamate derivatives exhibit good antifungal activity against Colletotrichum gloeosprioides and Fusarium oxysporum, F. proliferatum, Fusarium solani, Geotrichum candidum, Penicillium digitatum, Penicillium italicum, Pyricularia grisea.
Organic & Biomolecular Chemistry published new progress about 1443278-79-2. 1443278-79-2 belongs to iodides-buliding-blocks, auxiliary class Pyrazole,Iodide,Amine, name is 4-Iodo-1-methyl-1H-pyrazol-5-amine, and the molecular formula is C4H6IN3, Application of 4-Iodo-1-methyl-1H-pyrazol-5-amine.
Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com