Augeri, David J. published the artcilePotent and Selective Non-Cysteine-Containing Inhibitors of Protein Farnesyltransferase, HPLC of Formula: 165534-79-2, the publication is Journal of Medicinal Chemistry (1998), 41(22), 4288-4300, database is CAplus and MEDLINE.
Potent and selective non-thiol-containing inhibitors of protein farnesyltransferase are described. FTI-276 was transformed into the pyridyl ether analog. The potency of the pyridyl ether was improved by modification of the biphenyl core to that of an o-tolyl substituted biphenyl core. In addition to 0.4 nM in vitro potency, this compound displayed 350 nM potency in whole cells as the parent carboxylic acid. The o-tolyl biphenyl core dramatically and unexpectedly enhanced the potency of other compounds
Journal of Medicinal Chemistry published new progress about 165534-79-2. 165534-79-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Benzene,Ester, name is Dimethyl 2-iodoterephthalate, and the molecular formula is C10H9IO4, HPLC of Formula: 165534-79-2.
Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com