Willenbrink, J. published the artcileMechanism of excretion of urinary contrast media, Recommanded Product: 2-(3,5-Diiodo-4-oxopyridin-1(4H)-yl)acetic acid, the publication is Naunyn-Schmiedebergs Archiv fuer Experimentelle Pathologie und Pharmakologie (1959), 16-18, database is CAplus.
3,5-Di-iodo-4-pyridone-N-acetic acid (I) and 3,5-diacetamido-2,4,6-triiodobenzoic acid (II) labeled with radioiodine were injected into Hippocampus cudae, which had no glomeruli. The excretion of I was 5 times that of II. Excretion through bile and intestine was insignificant. The excretion of I in rabbits decreased with a plasma concentration up to 10 mg. % and remained constant between 20 and 1280 mg. %. Blocking the tubules with 200 mg. % p-aminohippuric acid (PAH) caused a depression of excretion to 1-10 mg. %. The rate of excretion of II remained unchanged within the range of 1 to 1280 mg. % in the plasma and was not influenced by PAH.
Naunyn-Schmiedebergs Archiv fuer Experimentelle Pathologie und Pharmakologie published new progress about 101-29-1. 101-29-1 belongs to iodides-buliding-blocks, auxiliary class Pyridine,Iodide,Carboxylic acid,Ketone, name is 2-(3,5-Diiodo-4-oxopyridin-1(4H)-yl)acetic acid, and the molecular formula is C5H12O2, Recommanded Product: 2-(3,5-Diiodo-4-oxopyridin-1(4H)-yl)acetic acid.
Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com