[2+2+2] Cycloisomerisation of Aromatic Cyanodiynes in the Synthesis of Pyridohelicenes and Their Analogues was written by Klivar, Jiri;Jancarik, Andrej;Saman, David;Pohl, Radek;Fiedler, Pavel;Bednarova, Lucie;Stary, Ivo;Stara, Irena G.. And the article was included in Chemistry – A European Journal in 2016.Electric Literature of C10H6BrI The following contents are mentioned in the article:
We have developed a methodol. for the synthesis of pyridohelicenes and their analogs based on the Ni0-, CoI– or RhI-mediated intramol. [2+2+2] cycloisomerization of cyanodiynes. It allows for folding the linear precursors into the corresponding helical backbones comprising the newly formed pyridine unit in their central part. Along with racemic pyrido[n]helicenes (n=5,6,7) and their derivatives, both enantio- and diastereomerically pure pyrido[n]helicene-like mols. (n=5,6) were prepared by employing the chiral substrate-controlled cyclization of the corresponding enantiopure cyanodiynes. This study involved multiple reactions and reactants, such as 2-Bromo-1-iodonaphthalene (cas: 676267-05-3Electric Literature of C10H6BrI).
2-Bromo-1-iodonaphthalene (cas: 676267-05-3) belongs to iodide derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.Electric Literature of C10H6BrI
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com