Catalytic Preparation of 1-Aryl-Substituted 1,2,4-Triazolium Salts was written by Hutchinson, Scott M.;Ardon-Munoz, Luis G.;Ratliff, Margarita L.;Bolliger, Jeanne L.. And the article was included in ACS Omega in 2019.COA of Formula: C19H22F3IO3S The following contents are mentioned in the article:
1,4-Diaryl- and 1-aryl-4-alkyl-substituted 1,2,4-triazolium salts are convenient air-stable precursors to carbenes used both as organocatalysts or as ligands for transition metal complexes. Traditionally, they are prepared via a multistep synthetic pathway with the low-yielding formation of the triazolium ring occurring in the last step. An alternative two-step synthesis was developed involving the conversion of a primary amines or aniline derivatives to the corresponding 4-substituted triazoles followed by a copper-catalyzed arylation with diaryliodonium salts. This transition metal-catalyzed arylation can be carried out under mild conditions in acetonitrile and is tolerant toward both water and oxygen. Addnl., the high functional group tolerance of the protocol described here gives easy access to triazolium salts containing heterocyclic substituents or sulfides. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3COA of Formula: C19H22F3IO3S).
Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.COA of Formula: C19H22F3IO3S
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com