Enantioselective Copper-Catalyzed Arylation-Driven Semipinacol Rearrangement of Tertiary Allylic Alcohols with Diaryliodonium Salts was written by Lukamto, Daniel H.;Gaunt, Matthew J.. And the article was included in Journal of the American Chemical Society in 2017.Application In Synthesis of Mesityl(p-tolyl)iodonium trifluoromethanesulfonate The following contents are mentioned in the article:
In the presence of a bis(phenyloxazoline)propane copper(II) triflate complex and 2,6-di-tert-butylpyridine in CH2Cl2, cyclic allylic alcs. such as I underwent diastereoselective and enantioselective tandem arylation and semipinacol rearrangements with aryl(mesityl)iodonium or diaryliodonium hexafluorophosphates to yield nonracemic aryl spirocyclic ketones such as II in 61-99% yields, 3:1->20:1 dr, and in 81:19-99.5:0.5 er. II underwent diastereoselective ketone reduction, reductive amination, and Baeyer-Villiger oxidation reactions to give products such as spirocyclohexaneindenes III (R = 3-BrC6H4CH2NH, HO) as single diastereomers. The structure of II and of other aryl spirocyclic ketones were determined by X-ray crystallog. This study involved multiple reactions and reactants, such as Mesityl(p-tolyl)iodonium trifluoromethanesulfonate (cas: 1204518-02-4Application In Synthesis of Mesityl(p-tolyl)iodonium trifluoromethanesulfonate).
Mesityl(p-tolyl)iodonium trifluoromethanesulfonate (cas: 1204518-02-4) belongs to iodide derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Application In Synthesis of Mesityl(p-tolyl)iodonium trifluoromethanesulfonate
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com