A general and mild copper(I)-catalyzed three-component reaction of cyanamides, amines, and diaryliodonium triflates was written by Li, Jihui;Wang, Hongxing;Hou, Yifeng;Yu, Weiguang;Xu, Shuying;Zhang, Yucang. And the article was included in European Journal of Organic Chemistry in 2016.Computed Properties of C19H22F3IO3S The following contents are mentioned in the article:
A highly efficient copper(I)-catalyzed three-component reaction of cyanamides R1NHCN, amines R2R3NH, and diaryliodonium triflates Ar2IOTf was developed for the synthesis of guanidines R1NHC(NR2R3):NAr [R1 = aryl, Bu, iPr, Cy, cyclopropyl; R2 = Bu, iPr, tBu, PhCH2, Cy, cyclopropyl; R3 = H; R2-R3 = (CH2)5, (CH2)4]. The mild reaction is catalyzed by CuCl/bipy composition in the presence of K2CO3 as a base, accommodating both aromatic and aliphatic amines and provides the products in good yields with good functional group tolerance. Moreover, it was demonstrated that C-H activation of the arenes could be realized for the direct preparation of guanidines. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Computed Properties of C19H22F3IO3S).
Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.Computed Properties of C19H22F3IO3S
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com