Tandem Arylation/Friedel-Crafts Reaction of O-Hydroxy Bisbenzylic Alcohols with Diaryliodonium Salts: One Pot Synthesis of Unsymmetrical 9-Arylxanthenes was written by Mao, Song;Hua, Zerui;Wu, Xunshen;Yang, Yang;Han, Jianwei;Wang, Limin. And the article was included in ChemistrySelect in 2016.Product Details of 1204518-02-4 The following contents are mentioned in the article:
A one-pot synthesis of 9-arylxanthenes I (R1 = H, 2-Br, 4-t-Bu, 4-Me, 1,4-Me2, etc., R2 = H, R3 = Ph, 2-MeOC6H4, 4-FC6H4, 1-naphthyl, etc.; R1 = H, R2 = 2-F, 2-F3C, 2-EtO2C, etc.; R3 = Ph) from easily prepared o-hydroxy bisbenzylic alcs. II and diaryliodonium salts III (R4 = R2, 2,4,6-Me3) is reported. O-Hydroxy bisbenzylic alcs. were utilized to generate carbinols in-situ with diaryliodonium salts promoted by base. Carbinols were then subjected to Bronsted acid catalyzed cyclization to furnish 9-arylxanthenes. A variety of sym. and unsym. 9-aryxanthenes were prepared assisted by base and Bronsted acid under mild conditions in satisfactory yields (up to 95%). Furthermore, the procedure was capable of tolerating a wide range of substrates. This study involved multiple reactions and reactants, such as Mesityl(p-tolyl)iodonium trifluoromethanesulfonate (cas: 1204518-02-4Product Details of 1204518-02-4).
Mesityl(p-tolyl)iodonium trifluoromethanesulfonate (cas: 1204518-02-4) belongs to iodide derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Product Details of 1204518-02-4
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com