Nino, Patricia published the artcileEfficient three-component synthesis of diversely substituted tetrahydro-1H-cyclopenta[c]quinolines, Synthetic Route of 364-12-5, the publication is Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (2016), 55B(7), 854-881, database is CAplus.
The synthesis of highly functionalized substituted tetrahydro-1H-cyclopenta[c]quinoline and its reduced derivatives hexahydro-1H-cyclopenta[c]quinolines via Povarov reaction in high diastereoselectivity and high to moderate yields is described. In addition, the relative stereochem. of the α-substituent to the tetrahydroquinoline nitrogen, as well as the regioselectivity of reaction, is shown to depend upon subtle substituent effects on the aldehyde and aniline precursors. In most cases, a preference for the formation of endo diastereomeric adducts is observed but for reactions with ortho-substituted aldehydes, the formation of exo adducts is also observed The exo-diastereoselectivity is found to be higher when the bulky size of this ortho group increases. Preparation of ortho and diortho-substituted aromatic aldehyde precursors of the Povarov reaction is also reported.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 364-12-5. 364-12-5 belongs to iodides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Bromide,Iodide,Benzene, name is 5-Bromo-2-iodobenzotrifluoride, and the molecular formula is C7H3BrF3I, Synthetic Route of 364-12-5.
Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com