Blanksma, J. J. published the artcileSweet taste of 4-nitro-2-aminotoluene, 4-nitro-2-aminobenzoic acid, and 2-nitro-4-aminobenzoic acid, Recommanded Product: 4-Iodo-3-nitroaniline, the main research area is .
4,2-O2N(H2N)C6H3Me, m. 107°, is 330 times as sweet as sucrose. 2,4-O2N(H2N)C6H3Me, m. 78°, is tasteless with a faintly bitter after-taste. The Ac derivatives of the 2 isomers are tasteless. 4,2-O2N(AcHN)C6H3Me (1 g.) in 250 cc. H2O, oxidized with 1.6 g. KMnO4 in 100 cc. H2O (refluxing 3 hrs.), and the Ac derivative (m. 215°) hydrolyzed with concentrated HCl in EtOH, gives 4,2-O2N(H2N)C6H3CO2H, m. 264°, which is 25 times as sweet as sugar; the Ac derivative, the Me ester, and its Ac derivative, m. 144°, are tasteless. 2,4-O2N(H2N)C6H3CO2H, m. 239°, is 120 times as sweet as sucrose; the Na salt is also very sweet but the Ac derivative is tasteless. o-HOC6H4CO2H has a relative degree of sweetness of 4 but the Na salt is 28 times as sweet as sucrose. There is no noticeable relation between the sweet taste and the local anesthetic activity of these compounds
Recueil des Travaux Chimiques des Pays-Bas et de la Belgique published new progress about Sweetness. 105752-04-3 belongs to class iodides-buliding-blocks, name is 4-Iodo-3-nitroaniline, and the molecular formula is C6H5IN2O2, Recommanded Product: 4-Iodo-3-nitroaniline.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com