Wang, Cailan published the artcileMacrocyclic factor XIa inhibitors, Recommanded Product: 4-Iodo-3-nitroaniline, the main research area is macrocyclic phenylimidazole preparation factor XIa inhibitor anticoagulant thromboplastin; Activated partial thromboplastin time; FXIa; Factor XIa inhibitors; Thrombosis; aPTT.
A series of macrocyclic factor XIa (FXIa) inhibitors was designed based on an anal. of the crystal structures of the acyclic phenylimidazole compounds Further optimization using structure-based design led to inhibitors with pM affinity for FXIa, excellent selectivity against a panel of relevant serine proteases, and good potency in the activated partial thromboplastin time (aPTT) clotting assay.
Bioorganic & Medicinal Chemistry Letters published new progress about Anticoagulants. 105752-04-3 belongs to class iodides-buliding-blocks, name is 4-Iodo-3-nitroaniline, and the molecular formula is C6H5IN2O2, Recommanded Product: 4-Iodo-3-nitroaniline.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com