Wu, Qiuyue published the artcileSulfur-controlled and rhodium-catalyzed formal (3 + 3) transannulation of thioacyl carbenes with alk-2-enals and mechanistic insights, Product Details of C11H11IO3, the main research area is dihydrothiopyranone preparation; thiadiazole alkenal preparation denitrogenative transannulation rhodium catalyst.
A rhodium-catalyzed denitrogenative formal (3+3) transannulation of 1,2,3-thiadiazoles I (Ar = Ph, 2H-1,3-benzodioxol-5-yl, furan-2-yl, etc.) with alk-2-enals R3C(R2)=C(R1)CHO [R1 = H, Me; R2 = H, Me, 4-methoxyphenyl, cyclohexyl, etc.; R3 = H, Me,4-methylpent-3-en-1-yl; R2R3 = -(CH2)4-, -(CH2)6-, -(CH2)12-, etc.] is achieved, producing 2,3-dihydrothiopyran-4-ones II in moderate to excellent yields. An inverse KIE of 0.49 is obtained, suggesting the reversibility of the oxidative addition of thioacyl Rh(I) carbenes to alk-2-enals. The late-stage structural modifications of steroid compounds III are realized. Moreover, this study shows that thioacyl carbenes have different reactivities to those of α-oxo and α-imino carbenes, and highlight the importance of heteroatoms in deciding the reactivities of heterovinyl carbenes.
Organic & Biomolecular Chemistry published new progress about Cyclization ((3+3)). 63131-30-6 belongs to class iodides-buliding-blocks, name is Ethyl 3-(4-iodophenyl)-3-oxopropanoate, and the molecular formula is C11H11IO3, Product Details of C11H11IO3.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com