Scheipers, Ina published the artcilePalladium-Catalyzed Decarboxylative γ-Arylation for the Synthesis of Tetrasubstituted Chiral Allenes, Synthetic Route of 2100-25-6, the main research area is alkynoic acid aryl iodide enantioselective palladium catalyst decarboxylative arylation; chiral tetrasubstituted allene stereoselective preparation; allenes; asymmetric synthesis; chirality transfer; cross-coupling; palladium.
An enantiospecific palladium-catalyzed decarboxylative coupling of acyclic β,γ-alkynoic acids with various aryl iodides to chiral tetrasubstituted allenes is described. The coupling reaction comprises a decarboxylative γ-palladation of α,α-disubstituted carboxylic acids to provide the tetrasubstituted allenes with complete point-to-axial chirality transfer in excellent yields.
Angewandte Chemie, International Edition published new progress about Allenes Role: SPN (Synthetic Preparation), PREP (Preparation). 2100-25-6 belongs to class iodides-buliding-blocks, name is 3-Iodo-1,2,4,5-tetramethylbenzene, and the molecular formula is C10H13I, Synthetic Route of 2100-25-6.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com