Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. 626-01-7, formula is C6H6IN, Name is 3-Iodoaniline. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Safety of 3-Iodoaniline.
Wang, Jun-Ling;Ma, Sen;Zhang, Pei-Zhi;Jia, Ai-Quan;Zhang, Qian-Feng research published 《 Syntheses and Crystal Structures of Methyl N-Substituted-N’-Cyanocarbamimidothioates Derived from Dimethyl N-Cyanodithioiminocarbonate》, the research content is summarized as follows. Reaction of di-Me N-cyanodithioiminocarbonate and aryl-/alkyl-amine compounds RNH2 (R = Ph, benzyl, Bu, etc.) in the refluxing ethanol solution afforded the Me N-substituted-N’-cyanocarbamimidothioates RNHC(SMe)=NCN in good yields. Me N-substituted-N’-cyanocarbamimidothioates were characterized by proton NMR (1H NMR) and IR spectroscopies, of which the structures of compounds RNHC(SMe)=NCN (R = Ph, benzyl, 4-chlorophenyl) were established by X-ray crystallog., showing that weak hydrogen-bonding interactions exist in compounds RNHC(SMe)=NCN (R = Ph, benzyl, 4-chlorophenyl). RNHC(SMe)=NCN (R = Ph) crystallizes in the orthorhombic space group Pbca, with a = 6.997(2), b = 7.395(2), c = 36.112(11) Å, and Z = 8. The unit cell of RNHC(SMe)=NCN (R = benzyl) has a monoclinic P21/c symmetry with the cell parameters a = 5.8717(12), b = 4.6598(9), c = 37.799(9) Å, β = 91.126(6)°, and Z = 4. Compound RNHC(SMe)=NCN (R = 4-chlorophenyl) crystallizes in the orthorhombic space group Pbca, with a = 7.123(3), b = 7.374(3), c = 38.538(16) Å, and Z = 8.
Safety of 3-Iodoaniline, 3-Iodoaniline is a useful research compound. Its molecular formula is C6H6IN and its molecular weight is 219.02 g/mol. The purity is usually 95%.
3-Iodoaniline is a fatty acid that is used in analytical methods to measure the concentration of human serum in blood. It can be used to estimate the population growth rate, with a half-life of about 13 hours. 3-Iodoaniline reacts with hydrogen bond and proton to form a reaction solution, which can be catalyzed by palladium-catalyzed coupling and suzuki coupling reactions. The activation energies for these reactions are typically in the range of 4-8 kcal/mol. The chemical ionization technique is a type of mass spectrometry that is used to determine kinetic data for this compound. Hydrochloric acid can be added as an acid catalyst to increase the rate of reaction and generate more accurate kinetic data., 626-01-7.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com