Zhang, Xu; Huang, Yu-Mei; Qin, Hua-Li; Zhang, Baoguo; Rakesh, K. P.; Tang, Haolin published their research in ACS Omega in 2021. The article was titled 《Copper-Promoted Conjugate Addition of Carboxylic Acids to Ethenesulfonyl Fluoride (ESF) for Constructing Aliphatic Sulfonyl Fluorides》.Computed Properties of C7H5IO2 The article contains the following contents:
A CuO-promoted direct hydrocarboxylation of ethenesulfonyl fluoride (ESF) was developed using carboxylic acid as a nucleophile under mild conditions. A variety of mols. containing both ester group and aliphatic sulfonyl fluoride moiety exhibit great potential in medicinal chem. and chem. biol. Furthermore, the modification of the known drugs Ibuprofen and Aspirin was also demonstrated. In addition to this study using 4-Iodobenzoic acid, there are many other studies that have used 4-Iodobenzoic acid(cas: 619-58-9Computed Properties of C7H5IO2) was used in this study.
4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Computed Properties of C7H5IO2
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com