Formula: C7H5IO2In 2022 ,《Transformation of Thioacids into Carboxylic Acids via a Visible-Light-Promoted Atomic Substitution Process》 was published in Organic Letters. The article was written by Wang, Rui; Xie, Kai-jun; Fu, Qiang; Wu, Min; Pan, Gao-feng; Lou, Da-wei; Liang, Fu-Shun. The article contains the following contents:
A visible-light-promoted at. substitution reaction for transforming thiocacids into carboxylic acids with DMSO as the oxygen source was developed, affording various alkyl and aryl carboxylic acids in over 90% yields. The at. substitution process proceeded smoothly through a photochem. reactivity of the formed hydrogen bonding adduct between thioacids and DMSO. DMSO-involved proton-coupled electron transfer (PCET), and simultaneously generating thiyl and hydroxyl radicals were proposed to be key species for realizing the transformation.4-Iodobenzoic acid(cas: 619-58-9Formula: C7H5IO2) was used in this study.
4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Formula: C7H5IO2
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com