Yadav, Mangal S.’s team published research in Synthesis in 2021 | CAS: 88-67-5

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Related Products of 88-67-5Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.

《N -Acylbenzotriazoles as Proficient Substrates for an Easy Access to Ureas, Acylureas, Carbamates, and Thiocarbamates via Curtius Rearrangement Using Diphenylphosphoryl Azide (DPPA) as Azide Donor》 was written by Yadav, Mangal S.; Singh, Sumt K.; Agrahari, Anand K.; Singh, Anoop S.; Tiwari, Vinod K.. Related Products of 88-67-5This research focused onurea or acylurea preparation; acylbenzotriazole amine or amide Curtius rearrangement DPPA; carbamate or thiocarbamate preparation; phenol or thiol acylbenzotriazole Curtius rearrangement DPPA. The article conveys some information:

A diverse range of ureas RNHC(O)NHC(O)R1 [R = Ph, 2-IC6H4, 3-BrC6H4, etc.; R1 = Ph, 2-IC6H4], N-acylureas R1NHC(O)NHR2 [R1 = Ph, 3-BrC6H4, 2-MeOC6H4, etc; R2 = Ph, 2-BrC6H4, 2-IC6H4], carbamates and thiocarbamates R1NHC(O)R2 [R1 = Ph, 3,5-di-MeC6H3, 3-MeC6H4; R2 = OPh, SPh, S(2-MeC6H4), etc.] was synthesized in good to excellent yields by reacting N-acylbenzotriazoles individually with amines/amides/phenols/thiols in the presence of diphenylphosphoryl azide (DPPA) as a suitable azide donor in anhydrous toluene at 110°C for 3-4 h. In this route, DPPA was found to be a good alternative to trimethylsilyl azide and sodium azide for the azide donor in Curtius degradation The high reaction yields, one-pot and metal-free conditions, straightforward nature, easy handling, use of readily available reagents and in many cases avoidance of column chromatog. were the notable features of the devised protocol. The results came from multiple reactions, including the reaction of 2-Iodobenzoic acid(cas: 88-67-5Related Products of 88-67-5)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Related Products of 88-67-5Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com