In 2022,Ding, Decai; Dong, Haiyan; Wang, Chuan published an article in CCS Chemistry. The title of the article was 《Nickel-catalyzed reductive electrophilic ring-opening of benzofurans with alkyl halides》.Category: iodides-buliding-blocks The author mentioned the following in the article:
Developed an electrophilic ring-opening reaction, which was beyond the strained small ring system. Under reductive nickel catalysis, ring-opening of diverse benzofurans via endocyclic inert carbon-oxygen bond cleavage was achieved with an array of inactivated secondary and tertiary alkyl halides as coupling partners, allowed for the preparation of a series of (E)-o-alkenylphenols with excellent E/Z-selectivity and high functional tolerance. The utility of this method were further demonstrated through derivatizations of the ring-opening products using the o-hydroxyl group as a functional handle, providing various organic compounds in good to high efficiency. In the experimental materials used by the author, we found tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3Category: iodides-buliding-blocks)
tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3) is one of organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Oceanic alkyl iodides are believed to be the principal source of atmospheric iodine.Category: iodides-buliding-blocks
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com