The author of 《Trideuteromethylation Enabled by a Sulfoxonium Metathesis Reaction》 were Shen, Zuyuan; Zhang, Shilei; Geng, Huihui; Wang, Jiarui; Zhang, Xinyu; Zhou, Anqi; Yao, Cheng; Chen, Xiaobei; Wang, Wei. And the article was published in Organic Letters in 2019. Product Details of 1774-47-6 The author mentioned the following in the article:
A conceptually novel sulfoxonium metathesis reaction between TMSOI and cost-effective DMSO-d6 is developed for the efficient generation of a new trideuteromethylation reagent TDMSOI. The new reagent TDMSOI is produced highly efficiently by simply heating a mixture of TMSOI and DMSO-d6 and directly used for subsequent trideuteromethylation in a “”one-pot”” operation. The preparative power of the new versatile reagent and the “”one-pot”” protocol is demonstrated by its use to install the -CD3 moiety into broad functionalities including phenols, thiophenols, acidic amines, and enolizable methylene units in high yield and at a useful level of deuteration (>87% D). In the part of experimental materials, we found many familiar compounds, such as Trimethylsulfoxonium iodide(cas: 1774-47-6Product Details of 1774-47-6)
Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.Product Details of 1774-47-6
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com