Ming, Xiao-Xia; Wu, Shuai; Tian, Ze-Yu; Song, Jia-Wei; Zhang, Cheng-Pan published their research in Organic Letters in 2021. The article was titled 《Pd/Cu-Catalyzed Vinylation of Terminal Alkynes with (2-Bromoethyl)diphenylsulfonium Triflate》.Safety of 1,2-Diiodoethane The article contains the following contents:
The potential of (2-bromoethyl)diphenylsulfonium triflate to be a powerful vinylation reagent was determined by the Sonogashira cross-coupling reactions with terminal alkynes RCCH (R = Ph, thiophen-3-yl, 4,4-dimethyl-3,4-dihydro-2H-1-benzothiopyran-6-yl, etc.). The vinylation proceeded smoothly at 25°C under Pd/Cu catalysis to afford a variety of 1- and 2-unsubstituted 1,3-enynes RCCCH=CH2 in moderate to excellent yields. This protocol represents the first application of (2-haloethyl)diphenylsulfonium triflates X(CH2)2S+(C6H5)2.-OTf (X = Br, F, OTs) and 5-(2-bromoethyl)-5H-thianthren-5-ium triflate as a CH=CH2 transfer source in organic synthesis. In the experimental materials used by the author, we found 1,2-Diiodoethane(cas: 624-73-7Safety of 1,2-Diiodoethane)
1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Oceanic alkyl iodides are believed to be the principal source of atmospheric iodine.Safety of 1,2-Diiodoethane
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com