Reference of Trimethylsulfoxonium iodideIn 2019 ,《Synthesis of Furoxans and Isoxazoles via Divergent [2 + 1 + 1 + 1] Annulations of Sulfoxonium Ylides and tBuONO》 was published in Organic Letters. The article was written by Tang, Zhonghe; Zhou, Yao; Song, Qiuling. The article contains the following contents:
A simple method for the divergent assembly of furoxans and isoxazoles in which the [2 + 1 + 1 + 1] annulation reaction of sulfoxonium ylides is reported. When the reaction was performed using t-BuONO as the nitrogen source without metal catalyst, the desired furoxans were obtained in decent yields with wide substrate scope. Isoxazoles bearing three carbonyl groups were achieved when the reaction was conducted using Cu(TFA)2 as catalyst. In addition to this study using Trimethylsulfoxonium iodide, there are many other studies that have used Trimethylsulfoxonium iodide(cas: 1774-47-6Reference of Trimethylsulfoxonium iodide) was used in this study.
Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.Reference of Trimethylsulfoxonium iodide
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com