In 2022,Forni, Jose A.; Gandhi, Vir H.; Polyzos, Anastasios published an article in ACS Catalysis. The title of the article was 《Carbonylative Hydroacylation of Styrenes with Alkyl Halides by Multiphoton Tandem Photoredox Catalysis in Flow》.Related Products of 301673-14-3 The author mentioned the following in the article:
The photocatalytic carbonylative hydroacylation of styrenes (R1)R2C=CH2 (R1 = H, Ph, Me, Et; R2 = Ph, naphthalen-2-yl, pyridin-2-yl, thiophen-2-yl, etc.) with inactivated alkyl halides RX (R = Cyclohexyl, cyclopentyl, n-Bu, i-Pr, etc.; X = Br, I) was reported. This protocol unifies the visible-light multiphoton catalytic cycle of [Ir(ppy)2(dtb-bpy)]+ with flow chem. to engage energy-demanding alkyl bromides and iodides at moderate pressures of carbon monoxide. The mild and practical methodol. was employed to prepare a diverse array of 43 unsym. dialkyl ketones RC(O)CH2CH(R1)R2 from primary, secondary, and tertiary inactivated alkyl halides. The application of flow chem. technol. to achieve spatially resolved chemoselectivity and broad functional group tolerance for the mild generation of functionalized C(sp3)-rich ketone products was demonstrated. The experimental process involved the reaction of tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3Related Products of 301673-14-3)
tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the SimmonsSmith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Related Products of 301673-14-3
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com