Pei, Xiaoyan; Xiang, Deng; Luo, Zhengxiu; Lei, Fukun; Guo, Zhanglong; Liu, Dong; Zhao, Zhigang; Ran, Maofei; Dai, Tao published an article in 2021. The article was titled 《Catalytic performance of palladium nanoparticles encapsulated within nitrogen-doped carbon during Heck reaction》, and you may find the article in Journal of Catalysis.Application In Synthesis of 1-Bromo-4-iodobenzene The information in the text is summarized as follows:
The Confinement effect is an effective strategy for enhancing the performance of catalysts during various reactions. We developed a strategy to encapsulating Palladium nanoparticles with a dopamine-derived N-doped multilayer carbon shell to catalyze the Heck reaction between iodobenzene and carbon-carbon double-bond compounds (styrene and Me acrylate). The catalytic performances of Pd nanoparticles encapsulated within a N-doped carbon layer (Pd@N-C) and those attached to the external surface of such a layer (Pd/N-C) were evaluated and compared. Pd@N-C exhibited a lower reaction activation energy (78 kJ/mol) than that of Pd/N-C (106 kJ/mol). Thus, the activity of Pd@N-C during the Heck reaction between iodobenzene and Me acrylate was approx. 20 times higher than that of Pd/N-C-200. The results of thermal filtration and recycling tests indicated that Pd@N-C showed a lower degree of leaching than that of Pd/N-C-200 owing to the spatial restriction effect of the cavity in the case of the former. Hence, the superior catalytic performance of Pd@N-C can be ascribed to the confinement of the Pd nanoparticles within the N-doped carbon layer. Finally, we useCinnamatesd these catalysts to synthesize a range of para-substituted iodobenzene derivatives, thus demonstrating the potential of Pd-encapsulating catalysts for use in the Heck reaction on the tech. scale. The experimental part of the paper was very detailed, including the reaction process of 1-Bromo-4-iodobenzene(cas: 589-87-7Application In Synthesis of 1-Bromo-4-iodobenzene)
1-Bromo-4-iodobenzene(cas: 589-87-7) is mainly used as the OLED pharmaceutical intermediate, as reagent for in situ desilylation and coupling of silylated alkynes, as substrate in copper-free Sonogashira coupling in aqueous acetone..Application In Synthesis of 1-Bromo-4-iodobenzene It is also used in synthesis of β,β,dibromostyrenes, as starting reagent in the total syntheses of ent-conduramine A and ent-7-deoxypancratistatin (alkaloids)
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com