Zhang, Mingjun; Yu, Mo; Wang, Ziwen; Liu, Yuxiu; Wang, Qingmin published an article in 2022. The article was titled 《Rapid Access to Aliphatic Sulfonamides》, and you may find the article in Organic Letters.Formula: C10H18INO2 The information in the text is summarized as follows:
Herein, a mild, rapid, straightforward method for visible-light-mediated sulfonamide ethylation to afford a diverse array of compounds with C(sp3)-sulfonamide skeletons RS(O)2N(R1)R2 (R = 4-phenylbutyl, 3,3-dimethylbutyl, 2-cyclobutylethyl, 4-(pyridin-2-yl)butyl, etc.; R1 = H, Ph, 2-oxooxolan-3-yl, benzyl, etc.; R2 = H, Me, phenyl) was reported. The method relies on inexpensive, abundant, com. available primary, secondary, and tertiary alkyl carboxylic acids I (R3 = 2-phenylethyl, 2,2-diphenylethyl, 2-(pyridin-3-yl)ethyl, pentyl, etc.) and alkyl iodides R4I (R4 = 2-cyclohexylethyl, pentyl, 4-(trimethylsilyl)butyl, hept-6-yn-1-yl, etc.) as substrates. The method has a broad substrate scope and potential utility for late-stage functionalization of natural products and synthetic medicines and can be expected to facilitate rapid structural diversification of bioactive mols. In addition to this study using tert-Butyl 4-iodopiperidine-1-carboxylate, there are many other studies that have used tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3Formula: C10H18INO2) was used in this study.
tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3) is one of organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Oceanic alkyl iodides are believed to be the principal source of atmospheric iodine.Formula: C10H18INO2
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com