In 2022,Javed; Khanam, Ariza; Mandal, Pintu Kumar published an article in Journal of Organic Chemistry. The title of the article was 《Glycosyl 3-Phenyl-4-pentenoates as Versatile Glycosyl Donors: Reactivity and Their Application in One-Pot Oligosaccharide Assemblies》.Product Details of 516-12-1 The author mentioned the following in the article:
Both glycoconjugates and oligosaccharides are important biomols. having significant roles in several biol. processes, and a new strategy for their synthesis is crucial. Here, we report a versatile N-iodosuccinimide/trimethylsilyl triflate (NIS/TMSOTf) promoted glycosidation approach with shelf-stable 3-phenyl-4-pentenoate glycosyl as a donor for the efficient synthesis of O/C-glycosides with free alcs., silylated alcs., and C-type nucleophile acceptors in good to excellent yields. The mild activation conditions and outstanding reactivity of Ph substituted pentenoate donors analogous to 4-pentenoate glycosyl donors enhance their applicability to various one-pot strategies for the synthesis of oligosaccharides, such as single-catalyst one-pot and acceptor reactivity-controlled one-pot strategies. The experimental process involved the reaction of 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Product Details of 516-12-1)
1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Product Details of 516-12-1
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com