Application In Synthesis of Trimethylsulfoxonium iodideIn 2019 ,《Ruthenium(II)-catalyzed selective C-H bond activation of imidamides and coupling with sulfoxonium ylides: an efficient approach for the synthesis of highly functional 3-ketoindoles》 was published in Organic Chemistry Frontiers. The article was written by Wu, Chenglin; Zhou, Jianhui; He, Guoxue; Li, Huihui; Yang, Qiaolan; Wang, Run; Zhou, Yu; Liu, Hong. The article contains the following contents:
Ruthenium-catalyzed selective C-H bond activation of imidamides and annulation of sulfoxonium ylides were achieved, which afforded a series of 3-ketoindole derivatives in good yields with good functional group compatibility. The catalytic system generated an indole scaffold by C-N and C-S bond cleavage. This reaction constitutes the first intermol. coupling of ylides with arenes to afford a 3-ketoindole skeleton by ruthenium-catalyzed C-H activation and annulation cascade. In the experiment, the researchers used many compounds, for example, Trimethylsulfoxonium iodide(cas: 1774-47-6Application In Synthesis of Trimethylsulfoxonium iodide)
Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides.Application In Synthesis of Trimethylsulfoxonium iodide
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com