In 2022,Chen, Bo; Yu, Kai; Wu, Xiao-Feng published an article in Organic & Biomolecular Chemistry. The title of the article was 《Visible-light-induced defluorinative carbonylative coupling of alkyl iodides with α-trifluoromethyl substituted styrenes》.Product Details of 301673-14-3 The author mentioned the following in the article:
A visible-light-mediated defluorinative carbonylative cross-coupling of alkyl iodides RI (R = Me, cyclopentyl, N-Boc azetidin-3-yl, etc.) with α-trifluoromethyl styrenes R1C(=CH2)CF3 (R1 = 4-benzyloxyphenyl, 3-methylphenyl, 2-naphthyl, etc.) has been developed. The reaction occurs at room temperature under blue light irradiation, and various gem-difluoroalkenes R1C(CH2C(O)R)=CF2 were obtained in moderate to good yields. Synthetic transformations of the obtained product were performed as well. In the experiment, the researchers used many compounds, for example, tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3Product Details of 301673-14-3)
tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the SimmonsSmith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Product Details of 301673-14-3
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com