Abu-Zeid, Y. M.’s team published research in J. Pharm. Sci. U. Arab. Rep. in 1965 | CAS: 3993-79-1

2-Amino-5-iodopyrimidin-4(1H)-one(cas: 3993-79-1) belongs to anime. Milder oxidation, using reagents such as NaOCl, can remove four hydrogen atoms from primary amines of the type RCH2NH2 to form nitriles (R―C≡N), and oxidation with reagents such as MnO2 can remove two hydrogen atoms from secondary amines (R2CH―NHR′) to form imines (R2C=NR′). Tertiary amines can be oxidized to enamines (R2C=CHNR2) by a variety of reagents.SDS of cas: 3993-79-1

The author of 《Synthesis of new heterocyclic basic derivatives of expected amebicidal activity》 were Abu-Zeid, Y. M.; Abu-Elela, Z.; Ghoneim, K. M.. And the article was published in J. Pharm. Sci. U. Arab. Rep. in 1965. SDS of cas: 3993-79-1 The author mentioned the following in the article:

Halogenated derivatives of the heterocyclic nuclei pyridine, quinoline (I), and pyrimidine (II) were prepared Sulfonation of 8-Cl-I with 6 parts 20% fuming H2SO4 gave the 5-sulfonic acid (III). All trials to brominate or iodinate III and its Na salt or Me ester failed: non-aqueous media, different temperatures with variable duration, and 48% HBr with Br in CH3COOH. Also sulfonation of 5-Br-8-Cl-I was not successful. The II derivatives prepared were: 2-NH2-4-OH-II, 2-NH2-4-Cl-II, 2-NH2-4-OH-II-5-sulfonic acid, and the 2 new compounds 2-NH2-5-iodo-4-OH-II (IV), and 2-NH2-4-Cl-5-iodo II (V). IV was prepared by refluxing mercuric acetate, isocytosine (modified method of Roblin, et al., CA 36, 25329), and iodine in dioxane at 70° for 2 hrs. The precipitate resulting on addition to 15% KI solution was washed and crystallized from CH3COOH; yield 89.6%. V was prepared by refluxing gently POCl3, dimethylaniline, and 5-iodoisocytosine for 3 hrs. On alkalinization with NH4OH, boiling, filtration, and concentration V separated on cooling; yield 48%. In addition to this study using 2-Amino-5-iodopyrimidin-4(1H)-one, there are many other studies that have used 2-Amino-5-iodopyrimidin-4(1H)-one(cas: 3993-79-1SDS of cas: 3993-79-1) was used in this study.

2-Amino-5-iodopyrimidin-4(1H)-one(cas: 3993-79-1) belongs to anime. Milder oxidation, using reagents such as NaOCl, can remove four hydrogen atoms from primary amines of the type RCH2NH2 to form nitriles (R―C≡N), and oxidation with reagents such as MnO2 can remove two hydrogen atoms from secondary amines (R2CH―NHR′) to form imines (R2C=NR′). Tertiary amines can be oxidized to enamines (R2C=CHNR2) by a variety of reagents.SDS of cas: 3993-79-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com