Rakshit, Amitava; Dhara, Hirendra Nath; Alam, Tipu; Dahiya, Anjali; Patel, Bhisma K. published an article in 2021. The article was titled 《Cu(II)-Promoted Cascade Synthesis of Fused Imidazo-Pyridine-Carbonitriles》, and you may find the article in Journal of Organic Chemistry.Product Details of 63069-48-7 The information in the text is summarized as follows:
A Cu(II)-promoted synthesis of an aza-fused N-heterocycle having a benz-imidazopyridine scaffold is developed via an addition-cyclization reaction followed by an Ullmann-type C-N coupling between o-iodoanilines and γ-ketodinitriles. This protocol features a broad substrate scope, giving products in 32-84% yields. The compounds show excellent photoluminescence properties having two absorption maxima in the region between 270-280 and 338-350 nm and emission maxima in the range of 502-533 nm. The HOMO-LUMO energy gap of 3.49-3.57 eV was determined using Gaussian 09 at the B3LYP/6-31G (d, p) basis set level. Authors also demonstrated a few postsynthetic modifications. In the experiment, the researchers used 4-Chloro-2-iodoaniline(cas: 63069-48-7Product Details of 63069-48-7)
4-Chloro-2-iodoaniline(cas: 63069-48-7) belongs to anime. The reaction of alkyl halides, R―X, where X is a halogen, or analogous reagents with ammonia (or amines) is useful with certain compounds. Not all alkyl halides are effective reagents; the reaction is sluggish with secondary alkyl groups and fails with tertiary ones. Its usefulness is largely confined to primary alkyl halides (those having two hydrogen atoms on the reacting site).Product Details of 63069-48-7
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com