In 2016,Nakayama, Yasuaki; Maeda, Yuichiro; Kotatsu, Masayuki; Sekiya, Ruriko; Ichiki, Masato; Sato, Takaaki; Chida, Noritaka published 《Enantioselective Total Synthesis of (+)-Neostenine》.Chemistry – A European Journal published the findings.Formula: C2H4I2 The information in the text is summarized as follows:
A chirality transfer approach using acyclic polyol intermediates for the synthesis of (+)-neostenine (1, I) has been developed. The sequential Overman/Claisen rearrangement of an allylic 1,2-diol was especially useful, installing two contiguous stereocenters with complete diastereoselectivity in a one-pot sequence. The SmI2-mediated cyclization and the subsequent chemoselective reduction of a lactam moiety accomplished the first enantioselective total synthesis of (+)-neostenine (1). In the experimental materials used by the author, we found 1,2-Diiodoethane(cas: 624-73-7Formula: C2H4I2)
1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the SimmonsSmith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Formula: C2H4I2
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com