《N-Iodosuccinimide as Bifunctional Reagent in (E)-Selective C(sp2)-H Sulfonylation of Styrenes》 was written by Pramanik, Milan; Choudhuri, Khokan; Mal, Prasenjit. Recommanded Product: 1-Iodopyrrolidine-2,5-dioneThis research focused onvinyl sulfone preparation regioselective stereoselective; styrene sulfonyl hydrazide sulfonylation iodosuccinimide bifunctional reagent. The article conveys some information:
Herein, the use of N-iodosuccinimide (NIS) as a bifunctional reagent for a regio- and (E)-selective C(sp2)-H sulfonylation reaction of styrenes is reported. Styrenes and sulfonyl hydrazides treated with NIS and potassium carbonate in ethanol at 70° resulted in (E)-vinyl sulfones exclusively with good to excellent yields. NIS, plays a dual role to generate sulfonyl radical from sulfonyl hydrazides at an initial stage and finally gives β-iodosulfone intermediate which is further converted to (E)-vinyl sulfones. Overall, a sustainable method for mild, metal free, convenient, one pot and direct synthesis of (E)-vinyl sulfones from styrenes are demonstrated via a C-S coupling reaction. The experimental process involved the reaction of 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Recommanded Product: 1-Iodopyrrolidine-2,5-dione)
1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Recommanded Product: 1-Iodopyrrolidine-2,5-dione
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com