In 2022,Manenti, Marco; Gusmini, Simone; Lo Presti, Leonardo; Silvani, Alessandra published an article in European Journal of Organic Chemistry. The title of the article was 《Exploiting Enantiopure β-Amino Boronic Acids in Isocyanide-Based Multicomponent Reactions》.Formula: C7H5IO2 The author mentioned the following in the article:
Various isocyanide-based multicomponent reactions prove to be highly reliable when β-substituted β-amino boronic esters are employed as the amine component, allowing the efficient synthesis of unprecedented peptidomimetics and heteroatom-rich boron-containing small mols. In particular, the scope of the Ugi reaction is widely exploited, to give a family of enantiopure β-substituted β-amido boronates. The Ugi-azide and the van Leusen reactions allow to joint together prominent pharmacophoric moieties, such as β-amino boronic acids on one side, and tetrazole or imidazole rings on the other side, realizing a successful application of the mol. hybridization concept. In the part of experimental materials, we found many familiar compounds, such as 2-Iodobenzoic acid(cas: 88-67-5Formula: C7H5IO2)
2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Formula: C7H5IO2 Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com