In 2022,Matheau-Raven, Daniel; Dixon, Darren J. published an article in Journal of Organic Chemistry. The title of the article was 《A One-Pot Synthesis-Functionalization Strategy for Streamlined Access to 2,5-Disubstituted 1,3,4-Oxadiazoles from Carboxylic Acids》.Product Details of 15854-87-2 The author mentioned the following in the article:
A one-pot 1,3,4-oxadiazole synthesis-arylation strategy for accessing 2,5-disubstituted 1,3,4-oxadiazoles I [R1 = 3-pyridyl, 4-MeC6H4, 1-phenylcyclopropyl, etc.; R2 = Ph, 4-pyridyl, morpholino, etc.], from carboxylic acids, N-isocyaniminotriphenylphosphorane (NIITP) and aryl iodides, was reported. The reaction sequence, featuring a second stage copper-catalyzed 1,3,4-oxadiazole arylation, was found to tolerate (hetero)aryl, alkyl, and alkenyl carboxylic acids, and (hetero)aryl iodide coupling partners. The effectiveness of the two-stage strategy was exemplified by the late-stage functionalization of five carboxylic acid-containing APIs, and, an extension to the synthesis of aminated 1,3,4-oxadiazoles using N-benzoyloxy amine coupling partners, was also demonstrated. In the experimental materials used by the author, we found 4-Iodopyridine(cas: 15854-87-2Product Details of 15854-87-2)
4-Iodopyridine(cas: 15854-87-2) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Product Details of 15854-87-2
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com